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KILL CANCER IN HOURS


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KILL CANCER IN HOURS

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Boffin discovers light can be used to destroy tumours

in just two hours

 

He combined a single jab with ultraviolet light that

causes cancerous cells to self destruct

 

Just one treatment stopped tumours growing, doubling

chances of survival

 

A CANCER expert has hit on a way to kill tumours in

two hours — using light.


The technique involves a single jab with a chemical

then a flash of ultraviolet.

 

Cancer cells in lab mice were found to self-destruct,

with up to 95 per cent dead in two hours.

 

Professor Matthew Gdovin revealed the cells — which he

injected with the chemical compound nitrobenzaldehyde

— turned too acidic to survive.

 

He said after patenting his “photodynamic” therapy:

“There are many different types of cancers.

 

“The one thing they have in common is their

susceptibility to this induced cell suicide.

 

“We are thinking outside the box and finding a way to

do what for many is simply impossible.”


Just one treatment stopped tumours growing, doubling

chances of survival


Just one treatment stopped tumours growing, doubling

chances of survival...

 

His lab tests showed amazing results against triple

negative breast cancer — one of the most aggressive

forms.

 

Just one treatment stopped tumours growing, doubling

chances of survival.

 

Prof Gdovin, of the University of Texas at San

Antonio, said that because the treatment is non-

invasive it is ideal for hard to reach cancers such as

in the spine or heart.
 

https://www.thesun.co.uk/news/1385404/light-can-kill-
cancer-in-just-two-hours/

 

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straycat19

UTSA researcher develops new, non-invasive method to wipe out cancerous tumors
 

  
(June 27, 2016) -- Matthew Gdovin, an associate professor in the UTSA Department of Biology, has developed a newly patented method to kill cancer cells. His discovery, described in research published in The Journal of Clinical Oncology, may tremendously help people with inoperable or hard-to-reach tumors, as well as young children stricken with cancer.

Gdovin’s top-tier research involves injecting a chemical compound, nitrobenzaldehyde, into the tumor and allowing it to diffuse into the tissue. He then aims a beam of light at the tissue, causing the cells to become very acidic inside and, essentially, commit suicide. Within two hours, Gdovin estimates up to 95 percent of the targeted cancer cells are dead.

“Even though there are many different types of cancers, the one thing they have in common is their susceptibility to this induced cell suicide,” he said.

Gdovin tested his method against triple negative breast cancer, one of the most aggressive types of cancer and one of the hardest to treat. The prognosis for triple negative breast cancer is usually very poor. After one treatment in the laboratory, he was able to stop the tumor from growing and double chances of survival in mice.

“All forms of cancer attempt to make cells acidic on the outside as a way to attract the attention of a blood vessel, which attempts to get rid of the acid,” he said. “Instead, the cancer latches onto the blood vessel and uses it to make the tumor larger and larger.”

Chemotherapy treatments target all cells in the body, and certain chemotherapeutics try to keep cancer cells acidic as a way to kill the cancer. This is what causes many cancer patients to lose their hair and become sickly. Gdovin’s method, however, is more precise and can target just the tumor.

In the past two years, he’s developed his photodynamic cancer therapy to the point where it’s non-invasive. It now requires just an injection of the nitrobenzaldehyde fluid followed by a flash of an ultraviolet light to cause the cancer-killing reaction. Gdovin has now begun to test the method on drug-resistant cancer cells to make his therapy as strong as possible. He’s also started to develop a nanoparticle that can be injected into the body to target metastasized cancer cells. The nanoparticle is activated with a wavelength of light that it can pass harmlessly through skin, flesh and bone and still activate the the cancer-killing nanoparticle.

Gdovin hopes that his non-invasive method will help cancer patients with tumors in areas that have proven problematic for surgeons, such as the brain stem, aorta or spine. It could also help people who have received the maximum amount of radiation treatment and can no longer cope with the scarring and pain that goes along with it, or children who are at risk of developing mutations from radiation as they grow older.

“There are so many types of cancer for which the prognosis is very poor,” he said. “We’re thinking outside the box and finding a way to do what for many people is simply impossible.” 
 
By Joanna Carver
 Public Affairs Specialist

 

Gdovin, Matthew J

Title: ASSOCIATE PROFESSOR
College: COLLEGE OF SCIENCE-DEAN
Department: COS BIOLOGY
Mailing Address: BIOLOGY - 01860
Building: BSB 1.03.26
Email: [email protected]
Phone: (210) 458-5768

Original Press Release University of Texas at San Antonio

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