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  • China rejects claim of illness at Wuhan lab in late 2019

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    China rejects claim of illness at Wuhan lab in late 2019

     

    China on Monday dismissed as "totally untrue" reports that three researchers in Wuhan went to hospital with an illness shortly before the coronavirus emerged in the city and spread around the globe.

     

    Since infecting its first victims in the central Chinese city in late 2019, the pathogen has afflicted almost every country in the world, killing more than 3.4 million people and pummelling national economies.

     

    Beijing has always fiercely fought the theory that it could have escaped from one of its laboratories.

     

    Citing a US intelligence report, the Wall Street Journal reported Sunday that the trio from the Wuhan Institute of Virology were affected as early as November 2019, suffering from "symptoms consistent with both COVID-19 and common seasonal illness".

     

    China disclosed the existence of an outbreak of pneumonia cases in Wuhan to the World Health Organization (WHO) on December 31, 2019.

     

    Asked about the reports on Monday, Foreign Ministry spokesman Zhao Lijian described them as "totally untrue".

     

    He told reporters that, according to a statement from the institute, it "had not been exposed to COVID-19 before December 30, 2019, and a "zero-infection" record is kept among its staff and graduate students so far".

     

    The coronavirus was, however, taken to the lab for study, according to Chinese authorities.

     

    The theory that the killer virus leaked from a Chinese lab was fuelled by, among others, the administration of former US president Donald Trump.

     

    But in March, after a four-week stay in Wuhan, a joint study by the WHO and Chinese experts deemed such an explanation "extremely unlikely".

     

    Experts favor the generally accepted theory of the natural transmission of the virus from an animal—probably a bat—to humans, through another animal that has not yet been identified.

     

    Some believe, however, that WHO specialists did not have enough space to work freely during their investigation in Wuhan.

     

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    ‘Much of the currently available information suggests that a lab-based origin of Covid-19 is plausible. There remains no sign of an intermediate animal host that could have passed the virus to humans in 2019. There is no evidence that live mammals were sold at the Wuhan seafood market in 2019, and none of hundreds of animal samples collected from that market had any trace of the virus. In other words, there is zero evidence that supports a zoonotic origin of the virus that excludes the involvement of research activity.

     

    “There are copious precedents of pathogens leaking from labs — the original 2003 SARS virus leaked up to six times from labs across three countries. Consider that the SARS research and animal infection experiments at the Wuhan Institute of Virology, for more than 10 years, were all performed at relatively low biosafety levels. It is currently not possible to tell from the genetic evidence whether the virus ever passed through a laboratory or a lab personnel. 

     

    “The question is: How did a virus, whose lineage is found only in southern China, make its way into humans in the metropolitan city of Wuhan, more than a thousand miles away? We know that the Wuhan Institute of Virology had possibly the greatest collection of SARS viruses from numerous trips across China. We know that they were working with a batch of viruses very closely related to SARS-CoV-2. Details of these viruses and the experiments performed with them have not been shared in a timely manner.”  Alina Chan, molecular biologist at the Broad Institute of MIT and Harvard

     

    “It is worthy of a careful, rigorous, unbiased, objective examination, based on relevant, verifiable data. There are a number of plausible scenarios embedded in this label, ‘lab leak,’ and importantly, they include an unrecognized infection of a well-intentioned lab worker attempting to recover or study new coronaviruses from bats. It does not imply malice or even necessarily awareness (of the accident). Lab accidents are much more common than any of us know, or would like to admit, and they occur worldwide and even in the most safe and secure labs. U.S. biosafety labs are by no means strangers to accidents; leaks of some of the most dangerous infectious agents have occurred at CDC and other U.S. government labs.”  David A. Relman, microbiologist at Stanford University

     

    “The following lines of circumstantial evidence are noteworthy:

    The outbreak occurred in Wuhan, a city of 11 million people that does not contain horseshoe-bat colonies, and that is tens of kilometers from, and outside the flight range of, the nearest known horseshoe-bat colonies. Furthermore, the outbreak occurred at a time of year when horseshoe bats are in hibernation.

     

    “The outbreak occurred in Wuhan, on the doorstep of the laboratory that conducts the world’s largest research project on horseshoe bat viruses and worked with the world’s closest sequenced relative of the outbreak virus. The laboratory actively searched for new horseshoe-bat viruses in horseshoe-bat colonies in caves in remote rural areas in Yunnan province, brought those new horseshoe-bat viruses to Wuhan, and then mass-produced, manipulated, and studied those new horseshoe-bat viruses, year-round, inside Wuhan.

     

    “Documentary evidence establishes that the bat-SARS-related-coronavirus projects at the Wuhan Institute of Virology used personal protective equipment (usually just gloves; sometimes not even gloves) and biosafety standards that would pose high risk of infection of field-collection, field-survey, or laboratory staff upon contact with a virus having the transmission properties of SARS-CoV-2.”  Richard Ebright, molecular biologist at Rutgers University

     

    https://www.politico.com/newsletters/politico-nightly/2021/05/19/experts-weigh-in-on-the-wuhan-lab-leak-hypothesis-492915

     

     

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    The Wuhan Lab Leak Question:  A Disused Chinese Mine Takes Center Stage

     

    On the outskirts of a village deep in the mountains of southwest China, a lone surveillance camera peers down toward a disused copper mine smothered in dense bamboo. As night approaches, bats swoop overhead.

     

    This is the subterranean home of the closest known virus on Earth to the one that causes Covid-19. It is also now a touchpoint for escalating calls for a more thorough probe into whether the pandemic could have stemmed from a Chinese laboratory.

     

    In April 2012, six miners here fell sick with a mysterious illness after entering the mine to clear bat guano. Three of them died.

     

    Chinese scientists from the Wuhan Institute of Virology were called in to investigate and, after taking samples from bats in the mine, identified several new coronaviruses.

     

    Now, unanswered questions about the miners’ illness, the viruses found at the site and the research done with them have elevated into the mainstream an idea once dismissed as a conspiracy theory: that SARS-CoV-2, the virus that causes Covid-19, might have leaked from a lab in Wuhan, the city where the first cases were found in December 2019.

     

    The lab researchers thus far haven’t provided full and prompt answers, and there have been discrepancies in some information they have released. That has led to demands by leading scientists for a deeper investigation into the Wuhan institute and whether the pandemic virus could have been in its labs and escaped.

     

    Even some senior public-health officials who consider that possibility improbable now back the idea of a fuller probe. They say a World Health Organization-led team had insufficient access in Wuhan earlier this year to reach its conclusion that a lab leak was “extremely unlikely.”

     

    Most of those calling for a fuller examination of the lab hypothesis say they aren’t backing it over the main alternative—that the virus spread from animals to humans outside a lab, in the kind of natural spillover that has become more frequent in recent decades. There isn’t yet enough evidence for either idea, they say, nor are the two incompatible. The virus could have been one of natural origin that was brought back to a laboratory in Wuhan—intentionally or accidentally—and escaped.

     

    A growing number, however, including the director-general of the WHO and a prominent U.S. researcher who has worked with the Wuhan Institute of Virology, agree that the WIV needs to provide more information about its work to categorically rule out a lab spill.

     

    The Wall Street Journal reported on Sunday that three WIV researchers became ill enough in November 2019 that they sought local hospital care, according to a previously undisclosed U.S. intelligence report, though officials expressed differing views over the strength of the evidence. In January, the State Department had said that several WIV researchers became sick in autumn 2019 “with symptoms consistent with both COVID-19 and common seasonal illness.”

     

    The Biden administration has recommended to the WHO that it lead a fuller investigation into the possibility of a lab leak, backing a call by WHO Director-General Tedros Adhanom Ghebreyesus, who has offered to deploy specialists. An investigation should include other laboratories in Wuhan, not just the WIV, and the team conducting it should include laboratory safety experts, according to a U.S. health official. “We should be able to look at biosafety records and interview staff members,” the official said.

     

    The matter is likely to be discussed during a meeting of the WHO’s decision-making body, the World Health Assembly, which started Monday. Diplomatic support for a lab investigation is thin. Few governments are eager to champion a probe that China could easily veto.

     

    Beijing would be sure to resist any such effort and has tightly controlled access to information thus far. It denies that SARS-CoV-2 came from one of its labs or infected any WIV staff, and it wants the WHO to investigate whether the pandemic began outside Chinese borders. 

     

    “The U.S. keeps concocting inconsistent claims and clamoring to investigate labs in Wuhan,” China’s foreign ministry said in a written statement. “This fully shows that some people in the U.S. don’t care about facts and truth.” It cited the WHO-led team’s verdict on the implausibility of a lab leak and urged Washington to invite the WHO to investigate early U.S. cases.

    China’s National Health Commission and the WIV didn’t respond to requests for comment.

    Hidden mine

    Chinese authorities have obstructed independent efforts to investigate the mine, setting up a checkpoint nearby where unidentified men stopped several foreign journalists in recent weeks, on one occasion warning there were wild elephants ahead.

     

    A Journal reporter reached the mine by mountain bike but was later detained and questioned for about five hours by police, who deleted a cellphone photograph of the mine. Villagers told the reporter that local officials had warned them not to discuss the mine with outsiders.

    There was no sign of nearby villages being evacuated or any recent research activity at the mine. It was so overgrown that its entrance appeared to be inaccessible.

     

    A growing number of virologists, biologists and other leading scientists are calling for a closer examination of the lab hypothesis.

     

    Asked in a May 11 Senate hearing whether he thought the Covid-19 virus might have escaped from a Wuhan lab, Anthony Fauci, President Biden’s chief medical adviser, said, “That possibility certainly exists, and I am totally in favor of a full investigation of whether that could have happened.” Dr. Fauci is director of the National Institute of Allergy and Infectious Diseases, or NIAID, which has funded coronavirus research conducted with the WIV. He has said previously that the Covid-19 virus mostly likely evolved and jumped to humans in nature.

     

    Source:  https://www.wsj.com/articles/wuhan-lab-leak-question-chinese-mine-covid-pandemic-11621871125

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