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<rss version="2.0"><channel><title>News: General News</title><link>https://nsaneforums.com/news/general-news/page/320/?d=2</link><description>News: General News</description><language>en</language><item><title>This Observatory Will Help Reveal the Shape of the Universe</title><link>https://nsaneforums.com/news/general-news/this-observatory-will-help-reveal-the-shape-of-the-universe-r3646/</link><description><![CDATA[<div>
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					<strong>Opening next year, the Vera Rubin Observatory can show how dark matter affects the evolution of galaxies.</strong>
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								Next year, we will begin creating our most detailed map yet of the visible sky, as the Vera C. Rubin Observatory in Chile begins operations. The information it collects will far surpass previous data sets and is expected to yield significant breakthroughs in <a href="https://www.wired.com/tag/astrophysics/" rel="external nofollow">astrophysics</a>.
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							<p>
								The first star map can be traced back to the Greek astronomer and mathematician Hipparchus around 129 BC. While no record of his map exists today, the work he did marked the start of a long and important tradition. In 1989, the European Space Agency launched the High Precision Parallax Collecting Satellite (Hipparcos), punning on his name. In its three years of operation, it was able to measure with high precision the brightness, position, and motion of more than 110,000 stars in our Milky Way galaxy. ESA’s follow-up mission, Gaia, launched 24 years later, has increased that number to 2 billion, but its limited size means it can only peer so far into the universe. Next year, the new land-based observatory, named after Vera  Rubin—a pioneering astrophysicist of the 20th century—will begin operation, and it will have the ability to see much farther.
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							<p>
								This is because the observatory will be fitted with a large mirror—8.4 meters in diameter—that will help us detect not only objects in our galaxy that are too faint to be seen by Gaia, but also the dim light that reaches us from galaxies as far as billions of light years away. Its large field of view means that it will be able to image the entire sky above it every few days, after which it will start again. And it will keep doing this for 10 years, creating a series of maps that demonstrate the movement of these galaxies in space and time.
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								This data will help us understand more about the dark energy that is causing the universe to <a href="https://www.wired.com/story/the-universe-is-expanding-faster-than-it-should-why/" rel="external nofollow">expand</a> at an ever greater rate. It will also be used to probe the nature of dark matter. In the 1970s, it was Rubin who provided the first observational evidence that there is far more to the universe than the luminous objects we can see. By mapping the position and motion of stars at the outer edges of galaxies, she showed that the speed at which they spin around their galactic centers was too high for there not to be some unseen extra matter providing the additional gravitational pull necessary to keep them in orbit. In doing so, she proved the existence of  the mysterious substance called dark matter.
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								Dark matter accounts for about 85 per cent of all material in the universe—in 2022, the observatory named in Rubin’s honor will help us see how this substance affects the formation and evolution of galaxies, and even the shape of the universe itself.
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<p>
	<a href="https://www.wired.com/story/vera-rubin-observatory-dark-matter/" rel="external nofollow">This Observatory Will Help Reveal the Shape of the Universe</a>
</p>
]]></description><guid isPermaLink="false">3646</guid><pubDate>Wed, 15 Dec 2021 23:16:19 +0000</pubDate></item><item><title>Pfizer&#x2019;s anti-COVID drug still looks effective after further analysis</title><link>https://nsaneforums.com/news/general-news/pfizer%E2%80%99s-anti-covid-drug-still-looks-effective-after-further-analysis-r3645/</link><description><![CDATA[<header>
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		No deaths, ~80 percent drop in hospitalization compared to the placebo group.
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		<p>
			On Monday, pharmaceutical giant Pfizer released more data on its anti-COVID-19 drug, named Paxlovid. The company had released its initial data on the drug in early November, and it <a href="https://arstechnica.com/science/2021/11/pfizer-says-its-antiviral-pill-can-cut-89-of-covid-hospitalizations-and-deaths/" rel="external nofollow">looked extremely promising</a>: a drop in hospitalization and death of 89 percent in high-risk patients. But preliminary results like that don't always hold up, as we <a href="https://arstechnica.com/science/2021/11/womp-womp-efficacy-of-mercks-thor-inspired-covid-pill-crumbles-vexing-experts/" rel="external nofollow">saw with a drug from Merck</a>. But there's good news in this case: Paxlovid appears to be just as effective once more patients and numbers from a second trial are included.
		</p>

		<h2>
			On trial
		</h2>

		<p>
			Paxlovid inhibits a viral protein called a protease, which normally breaks chemical bonds in other viral proteins, converting them into their mature, functional forms. This processing is needed before the virus is able to copy its own genome, so inhibiting the protease should block viral reproduction.
		</p>

		<p>
			 
		</p>

		<p>
			Pfizer started at least two clinical trials with Paxlovid. One involved unvaccinated individuals who are at high risk from COVID-19 due to age or health issues. The second trial involved moderate risks: either unvaccinated individuals with no risk factors, or those who have been vaccinated but are at elevated risk. In both trials, treatments started within days of a confirmed infection.
		</p>

		<p>
			 
		</p>

		<p>
			The initial data Pfizer released last month came from an interim analysis of the high-risk trial. These are done by outside experts, who check to see whether the treatment is either causing severe problems or is clearly effective. In either case, the trial would be stopped early. In its new release, Pfizer now has additional data from the high-risk trial and initial data from the moderate-risk group.
		</p>

		<p>
			 
		</p>

		<p>
			In the high-risk group trial, there's now data from over 2,000 participants. And the results are in line with what was seen earlier. Less than 1 percent of the people who received the drug were hospitalized, compared to 6.5 percent of the placebo control group. Nobody receiving the drug died, while nine in the placebo group did. The drug appeared roughly equally effective when administered as late as five days after symptom onset.
		</p>

		<p>
			 
		</p>

		<p>
			Overall, there was a 94 percent reduction in relative risk among those over the age of 65. There's also evidence the drug reduced viral load, although this was a complicated analysis that's difficult to evaluate based on the information in a press release.
		</p>

		<p>
			 
		</p>

		<p>
			Among the moderate-risk patients, data is only available on 673 participants so far. But the numbers here also look good: a 70 percent reduction in hospitalization and no deaths in the treatment group. No one died in either the treatment or placebo groups, and the rate of hospitalizations was lower in the placebo group than in the placebo group of the high-risk trial, as you'd expect.
		</p>

		<h2>
			But how do they feel?
		</h2>

		<p>
			There's good and bad news on the more subjective measures. Reports of side effects were the good news, in that they were roughly equivalent in the treatment and placebo groups. In fact, slightly more people who received the placebo dropped out of the study due to reported side effects.
		</p>

		<p>
			 
		</p>

		<p>
			What's less good is that Paxlovid didn't help people feel much better. The moderate-risk trial asked patients to report if they experienced an alleviation of symptoms from their treatments and checked whether this was sustained over four days. There was no significant difference between those receiving Paxlovid and those receiving placebo by this measure.
		</p>

		<p>
			 
		</p>

		<p>
			Still, from a public health perspective, avoiding the need for hospitalization would be a very significant change, as this has the potential to reduce the strain that the health care system experiences during surges in infections. And Pfizer has already tested the drug against the variant of protease found in the omicron version of SARS-CoV-2, finding it binds to the protease effectively. The only obvious downside is that Paxlovid won't be much help for a while, as the company doesn't expect it will be able to produce that many doses until sometime in the new year.
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</p>

<p>
	<a href="https://arstechnica.com/science/2021/12/pfizers-anti-covid-drug-still-looks-effective-after-further-analysis/" rel="external nofollow">Pfizer’s anti-COVID drug still looks effective after further analysis</a>
</p>
]]></description><guid isPermaLink="false">3645</guid><pubDate>Wed, 15 Dec 2021 23:13:28 +0000</pubDate></item><item><title>Arctic heat record is like Mediterranean, says UN</title><link>https://nsaneforums.com/news/general-news/arctic-heat-record-is-like-mediterranean-says-un-r3636/</link><description><![CDATA[<p>
	<strong>The highest temperature ever recorded in the Arctic, 38C (100F), has been officially confirmed, sounding "alarm bells" over Earth's changing climate.</strong>
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<p>
	<br />
	The World Meteorological Organization (WMO) on Tuesday verified the record, reported in the Siberian town of Verkhoyansk on 20 June last year.
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<p>
	 
</p>

<p>
	The temperature was 18C higher than the area's average daily maximum for June.
</p>

<p>
	<br />
	The WMO, a UN agency, said the extreme heat was "more befitting the Mediterranean than the Arctic".
</p>

<p>
	<br />
	It is the first time the agency has included the Arctic Circle in its archive of extreme weather reports.
</p>

<p>
	<br />
	The WMO said the 38C temperature was measured at a meteorological station during "an exceptional and prolonged Siberian heatwave".
</p>

<p>
	<br />
	Last year's extreme heat in the region contributed to the spread of wildfires, which swept across the forests and peatlands of northern Russia releasing record amounts of carbon.
</p>

<p>
	<br />
	While relatively common in summer months, high temperatures and strong winds made the fires unusually severe.
</p>

<p>
	<br />
	The high temperatures across Siberia led to "massive sea ice loss" and played a major role in 2020 being one of the three warmest years on record, the WMO said.
</p>

<p>
	 
</p>

<p>
	The WMO said its verification of the Verkhoyansk record highlighted how temperatures were increasing in a climatically important region of the world.
</p>

<p>
	<br />
	"This new Arctic record is one of a series of observations reported to the WMO Archive of Weather and Climate Extremes that sound the alarm bells about our changing climate," said WMO Secretary-General Petteri Taalas.
</p>

<p>
	<br />
	The agency said it had added the Arctic Circle to its World Weather and Climate Extremes archive under a new category for high temperatures in the region.
</p>

<p>
	<br />
	The Arctic is one of the fastest warming regions in the world, heating at more than twice the global average, the WMO said.
</p>

<p>
	<br />
	Warming in the Arctic is leading to the thawing of once permanently frozen permafrost below ground.
</p>

<p>
	<br />
	This is alarming scientists because as permafrost thaws, carbon dioxide and methane previously locked up below ground is released.
</p>

<p>
	<br />
	These greenhouse gases can cause further warming, and further thawing of the permafrost, in a vicious cycle known as positive feedback.
</p>

<p>
	<br />
	The higher temperatures also cause land ice in the Arctic to melt at a faster rate, leading to greater run-off into the ocean where it contributes to sea-level rise.
</p>

<p>
	<br />
	Human activity is contributing to a rise in world temperatures, and climate change now threatens every aspect of human life.
</p>

<p>
	<br />
	Left unchecked, humans and nature will experience catastrophic warming, with worsening droughts, greater sea level rise and mass extinction of species.
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<p>
	 
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<p>
	<strong><a href="https://www.bbc.com/news/science-environment-59649066" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3636</guid><pubDate>Tue, 14 Dec 2021 13:04:54 +0000</pubDate></item><item><title>Here's Why a Vital Amazon Web Services Region Went Down on Dec. 7</title><link>https://nsaneforums.com/news/general-news/heres-why-a-vital-amazon-web-services-region-went-down-on-dec-7-r3623/</link><description><![CDATA[<p>
	Amazon shares the results of its investigation into the 'service disruption' that AWS (and its customers) experienced on Dec. 7.
</p>

<p>
	<br />
	Amazon has explained why a vital Amazon Web Services (AWS) region, US-East-1, experienced what the company describes as a "service disruption" for about seven hours on Dec. 7.
</p>

<p>
	<br />
	The problems with US-East-1 affected many people's ability to connect to streaming platforms like Netflix, Disney+, and Amazon Prime Video; games like Valorant, League of Legends, and PUBG; apps like Tinder, Venmo, and Coinbase; and many other services that rely on AWS.
</p>

<p>
	<br />
	The sheer popularity of those services makes it relatively easy to tell when AWS is having problems—just try to stream a video, play a game, or use a mobile app connected to the nigh-ubiquitous platform. But it can be much more difficult to figure out why AWS is down.
</p>

<p>
	<br />
	Here's what Amazon says caused US-East-1's woes:
</p>

<p style="margin-left:40px;">
	<br />
	"At 7:30 AM PST, an automated activity to scale capacity of one of the AWS services hosted in the main AWS network triggered an unexpected behavior from a large number of clients inside the internal network. This resulted in a large surge of connection activity that overwhelmed the networking devices between the internal network and the main AWS network, resulting in delays for communication between these networks. These delays increased latency and errors for services communicating between these networks, resulting in even more connection attempts and retries. This led to persistent congestion and performance issues on the devices connecting the two networks."
</p>

<p style="margin-left:40px;">
	 
</p>

<p>
	The company also says that congestion "immediately impacted the availability of real-time monitoring data for our internal operations teams, which impaired their ability to find the source of congestion and resolve it," as well as their ability to explain the issue to AWS customers.
</p>

<p>
	 
</p>

<p>
	AWS is a sprawling platform that offers a broad range of products used by many companies to serve a variety of purposes. It's a wonder that it doesn't experience major outages more often—and that it was able to recover from this particular disruption as quickly as it did.
</p>

<p>
	 
</p>

<p>
	However, the incident still highlights the inherent risk associated with so many companies relying on AWS, especially since the nature of the network means that problems with the platform can hinder efforts to solve problems with the platform. (And that's when a single region's involved!)
</p>

<p>
	 
</p>

<p>
	Amazon even acknowledges that relying too much on just one AWS region can be a problem:
</p>

<p>
	 
</p>

<p style="margin-left:40px;">
	"Our Support Contact Center also relies on the internal AWS network, so the ability to create support cases was impacted from 7:33 AM until 2:25 PM PST. We have been working on several enhancements to our Support Services to ensure we can more reliably and quickly communicate with customers during operational issues. We expect to release a new version of our Service Health Dashboard early next year that will make it easier to understand service impact and a new support system architecture that actively runs across multiple AWS regions to ensure we do not have delays in communicating with customers."
</p>

<p>
	 
</p>

<p>
	More information about what caused the disruption to US-East-1, how Amazon's responding to the issue, and which services were affected can be found in the company's summary.
</p>

<p>
	 
</p>

<p>
	<strong><a href="https://www.pcmag.com/news/heres-why-a-vital-aws-region-went-down-on-dec-7" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3623</guid><pubDate>Sun, 12 Dec 2021 14:48:52 +0000</pubDate></item><item><title>Why F1&#x2019;s switch from 13-inch to 18-inch tires is important</title><link>https://nsaneforums.com/news/general-news/why-f1%E2%80%99s-switch-from-13-inch-to-18-inch-tires-is-important-r3608/</link><description><![CDATA[<div data-page="1">
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				Pirelli tells us about next year's racing rubber—and why that rubber is in F1.
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			<p>
				<img alt="15-thursday-yasmarina-2-800x533.jpg" class="ipsImage" data-ratio="74.03" height="479" width="720" src="https://cdn.arstechnica.net/wp-content/uploads/2021/12/15-thursday-yasmarina-2-800x533.jpg">
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							On the left, a 2021-spec 13-inch Formula One tire. To its right, a 2022-spec 18-inch F1 tire.
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							<a href="https://www.latimages.com/" rel="external nofollow">Steven Tee / LAT Images</a>
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				<aside>
					Pirelli provided flights to Austin and three nights in a hotel so we could attend the US Grand Prix. Ars does not accept paid editorial content.
				</aside>

				<p>
					 
				</p>

				<p>
					Formula One goes to Abu Dhabi this weekend. When the checkered flag waves and the fireworks fly on Sunday night, a thrilling season will end with either Lewis Hamilton or Max Verstappen emerging as this year's champion.
				</p>

				<p>
					 
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				<p>
					But the Abu Dhabi Grand Prix doesn't just mean the end of an exciting year of racing—it also marks the end of an era as the sport prepares for a radical change to its tires. For decades, F1 cars have run on 13-inch wheels, wrapped in tires with high-profile sidewalls. But as part of 2022's radical technical shakeup, the sport is now joining much of the rest of the racing world as it adopts 18-inch wheels and new, low-profile racing rubber.
				</p>

				<p>
					 
				</p>

				<p>
					There was a lot of freedom in wheel size and choice for F1's first few decades, which might shock those accustomed to the current sport's rigid and prescriptive rulebook. The move to standard 13-inch wheels happened in the 1980s at a time when 13-inch wheels were still often fitted to road cars—albeit smaller, cheaper ones.
				</p>

				<p>
					 
				</p>

				<p>
					The limit on wheel size was enacted as a way to stop teams from fitting ever-bigger brakes to the cars; a lot of overtaking happens in the braking zones, and a consequence of reduced stopping distances is that overtaking becomes much harder. This helpfully shows that complaints about the absence of overtaking in F1 are nothing new, and if you're wondering why officials didn't they just mandate the brake diameter in the same rulebook that mandated wheel diameter, that did eventually happen.
				</p>

				<p>
					 
				</p>

				<p>
					<img alt="GettyImages-1322158873-980x653.jpg" class="ipsImage" data-ratio="75.10" height="479" width="720" src="https://cdn.arstechnica.net/wp-content/uploads/2021/12/GettyImages-1322158873-980x653.jpg">
				</p>

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							Max Verstappen makes his tire aware of his frustration after it failed and cost him a race win in Azerbaijan this year. It was the second catastrophic tire failure of the race.
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						<div>
							Clive Rose/Getty Images
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				<p>
					For years, the choice of tires in F1 was also relatively open, with competition between tire manufacturers as recently as 2006. But since 2011, it's been a one-brand show after Pirelli won the contract to be the sport's sole tire supplier.
				</p>

				<p>
					 
				</p>

				<p>
					This has been a potentially perilous position for Pirelli. In a tire war, manufacturers and their partner teams work together to improve grip and durability, with the aim of getting to the end of the race before anyone else. But as the sole supplier, Pirelli was tasked by the F1 powers-that-be with delivering tires that would spice up the show. More often than not, we just got lots of complaints from drivers instead, particularly if a tire ruined their race.
				</p>

				<p>
					 
				</p>

				<p>
					"It's the biggest issue we have, because clearly we are the supplier and received a request from different stakeholders for F1: What is important is to have a great show to sell to the world," said Mario Isola, head of F1 and car racing at Pirelli. "For drivers, what is important is to have a lot of grip, no degradation or overheating, and push, push, push," he explained.
				</p>

				<p>
					 
				</p>

				<p>
					That led to meetings between Pirelli and the teams and drivers to agree on the characteristics for the tires. "For example, for next year, there is a request of overheating reduction, there's a request to have a wider working [temperature] range, and there is a request to have a delta time between compounds that is around 0.5 seconds per lap," Isola told me.
				</p>
			</div>
		</section>
	</div>

	<div>
		 
	</div>
</div>

<div>
	<img alt="GettyImages-1169841235-980x653.jpg" class="ipsImage" data-ratio="75.10" height="479" width="720" src="https://cdn.arstechnica.net/wp-content/uploads/2021/12/GettyImages-1169841235-980x653.jpg">
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<div data-page="2">
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						<div>
							If it were up to the drivers, the tires would have unlimited grip and never wear out. And if it were up to the race promoters, the tires would be fragile, and each car would require multiple pit stops to create more opportunities for strategy.
						</div>

						<div>
							MLADEN ANTONOV/AFP via Getty Images
						</div>
					</figcaption>
				</figure>

				<p>
					Pirelli will still bring three different compounds of tire to each race—a soft, a medium, and a hard—and we can expect them to be a bit more durable than the rubber that fans have witnessed in recent years. "It's not zero degradation," said Isola, "because zero degradation is not good for the show, and it's not encouraging any different strategy, but it is a compromise that is making more or less everybody happy."
				</p>

				<p>
					 
				</p>

				<p>
					The new tires will have the same tread width as before—305 mm at the front and 405 mm at the rear—but the overall diameter of the tire is increasing to 720 mm (from 660 mm). That means slightly larger (and differently shaped) contact patches.
				</p>

				<p>
					 
				</p>

				<p>
					The new tires have been developed using a mix of simulation and track testing, with specially modified cars meant to replicate <a href="https://arstechnica.com/cars/2021/07/heres-the-new-car-formula-1-hopes-will-improve-racing-in-2022/" rel="external nofollow">some of the other big technical changes coming to F1 in 2022</a>. There are a few things to look for. "The cooling system of the brake will be completely different compared to this year," Isola told me.
				</p>

				<p>
					 
				</p>

				<p>
					Until the end of this year, teams have played with brake cooling to heat the wheel rims and tires (F1 brakes operate at between 400-1,000° C, and that heat transfers to the wheel and tire). That changes next year. The brakes are staying the same size and will now be surrounded by much more air inside the rim. The cars will gain wheel covers, which will affect tire heating and cooling.
				</p>

				<p>
					 
				</p>

				<p>
					F1 engineers will also have to throw out most of what they've learned about setting up an F1 car's suspension, too. Not only are the new wheels and tires heavier, but currently, the hefty sidewalls on the 13-inch tires do most of the springing, something you'll regularly see in slow-motion replays. In 2022, that job goes back to the actual springs in the suspension.
				</p>

				<p>
					 
				</p>

				<p>
					<img alt="GettyImages-451893840-980x653.jpg" class="ipsImage" data-ratio="75.10" height="479" width="720" src="https://cdn.arstechnica.net/wp-content/uploads/2021/12/GettyImages-451893840-980x653.jpg">
				</p>

				<figure>
					<figcaption>
						<div>
							The move to 18-inch wheels has been under consideration for some time. In 2014, Pirelli and F1 tested 18-inch wheels before deciding not to move forward with the switch.
						</div>

						<div>
							Mark Thompson/Getty Images
						</div>
					</figcaption>
				</figure>

				<p>
					"We were a bit worried about the impact on curbs, especially on circuits with very high curbs," Isola told me, ironically just a couple of weekends before the curbs of the Losail International Circuit in Qatar (which doesn't usually host F1) <a href="https://www.racefans.net/2021/12/03/pirellis-investigation-into-qatar-tyre-failures-indicates-kerbs-caused-punctures/" rel="external nofollow">damaged several tires</a>. "But talking to the drivers, they reported no issues [with the 2022 tire]," Isola said. "They could drive without changing the driving lines and so on. So that's good feedback for us."
				</p>

				<p>
					 
				</p>

				<p>
					You may be wondering what Pirelli gets out of all of this. Yes, there's a marketing value, but the company could also spend that money on different kinds of advertising instead. But it seems Pirelli does find avenues for technology transfer, despite the radical differences between F1 and road cars.
				</p>

				<p>
					 
				</p>

				<p>
					"It is true that the tread compound is designed to work at 120° C—that is something that never happens on the road, unless you are crazy, and then the police will stop you very soon," Isola told me. "But there are a lot of other elements that we can use in Formula One. And we learn from that."
				</p>

				<p>
					 
				</p>

				<p>
					<img alt="GettyImages-1337083019-980x551.jpg" class="ipsImage" data-ratio="75.10" height="404" width="720" src="https://cdn.arstechnica.net/wp-content/uploads/2021/12/GettyImages-1337083019-980x551.jpg">
				</p>

				<figure>
					<figcaption>
						<div>
							F1 tire compounds might not be very road-relevant, but the tread pattern on wet tires, able to withstand aquaplaning at 180 mph (300 km/h), certainly is.
						</div>

						<div>
							Mario Renzi - Formula One/Formula One via Getty Images
						</div>
					</figcaption>
				</figure>

				<p>
					"In terms of vehicle models, in terms of materials, production processes, quality controls, indoor testing that is representative of what happened on track, obviously you can make the same for on-road tires—there are a lot of areas in which we develop technology that is applicable to road tires. It is not the tread compound because the tread compound is designed to last for 150 kilometers and 120 degrees," Isola explained.
				</p>

				<p>
					 
				</p>

				<p>
					"What is claimed in the Formula One is for sure the extreme limit—the acceleration, the top speed, the downforce," said Piero Misani, head of R&amp;D at Pirelli. "The lateral forces in F1 are by far the highest that you can have in any kind of car competition."
				</p>

				<p>
					 
				</p>

				<p>
					Some of that is due to materials. Misani said that Pirelli experimented with liquid polymers for the base of the tire compound and grip-promoting resins in F1 before transferring those ideas to its standard road tires, as well as a new hybrid cord construction.
				</p>

				<p>
					 
				</p>

				<p>
					Next year's move to much more road-relevant 18-inch low-profile tires should help that technology-transfer process. But mostly, let's hope the switch makes for good racing.
				</p>
			</div>
		</section>
	</div>
</div>

<p>
	 
</p>

<p>
	 
</p>

<p>
	<a href="https://arstechnica.com/cars/2021/12/why-f1s-switch-from-13-inch-to-18-inch-tires-is-important/" rel="external nofollow">Why F1’s switch from 13-inch to 18-inch tires is important</a>
</p>
]]></description><guid isPermaLink="false">3608</guid><pubDate>Fri, 10 Dec 2021 03:54:22 +0000</pubDate></item><item><title>Why global tech turns to Indian talent</title><link>https://nsaneforums.com/news/general-news/why-global-tech-turns-to-indian-talent-r3602/</link><description><![CDATA[<p>
	Twitter's new CEO Parag Agrawal is the latest alumnus of India's prestigious technical universities appointed to head a multi-billion-dollar US tech firm, and Shivani Nandgaonkar wants to follow in his footsteps.
</p>

<p>
	 
</p>

<p>
	The 22-year-old student at the Indian Institute of Technology Bombay —Agrawal's alma mater—has already been recruited by Google to become one of the thousands of IIT graduates at major American tech companies.
</p>

<p>
	 
</p>

<p>
	"When I heard about Parag, I was so happy," she said. "One IITian is also CEO of Google, Sundar Pichai. So this is my (stepping) stone now."
</p>

<p>
	Twitter's Agrawal is the youngest chief executive in the S&amp;P 500 at just 37.
</p>

<p>
	 
</p>

<p>
	Like Google-parent Alphabet's 49-year-old CEO Sundar Pichai, he left India after his IIT degree to pursue a postgrad in the United States before working at several American companies.
</p>

<p>
	 
</p>

<p>
	Other Indians at the highest corporate tech echelons include IBM's Arvind Krishna and Palo Alto Networks' Nikesh Arora—both IIT alumni—along with Satya Nadella of Microsoft and Shantanu Narayen at Adobe.
</p>

<p>
	 
</p>

<p>
	Executives and experts say that beyond the South Asian nation's sheer size, the phenomenon is due to multiple push-pull factors and skillsets including a culture of problem-solving, the English language, and relentless hard work.
</p>

<p>
	 
</p>

<p style="text-align:center;">
	<img alt="the-iit-network-was-es.jpg" class="ipsImage" data-ratio="73.89" height="478" width="720" src="https://scx1.b-cdn.net/csz/news/800a/2021/the-iit-network-was-es.jpg" />
</p>

<p style="text-align:center;">
	<span style="font-size:12px;"><em>The IIT network was established in 1950 by India's first prime minister Jawaharlal Nehru, who envisaged a pool of highly trained science and engineering graduates to help build the country.</em></span>
</p>

<p style="text-align:center;">
	 
</p>

<p>
	IIT graduate and Sun Microsystems co-founder Vinod Khosla believes that after growing up with multiple communities, customs and languages, Indians have the ability to "navigate complex situations".
</p>

<p>
	 
</p>

<p>
	"Educational competition in India and societal chaos helps hone their skills in addition to the rigorous technical education at the IITs," the billionaire venture capitalist told AFP.
</p>

<p>
	 
</p>

<p>
	<strong>'Creme de la creme'</strong>
</p>

<p>
	 
</p>

<p>
	Silicon Valley demands technical expertise, managing diverse communities, and entrepreneurship in the face of uncertainty from its top executives.
</p>

<p>
	"In innovation, you have to be able to break the rules, you're fearless. And... you can't survive a day in India without having to break one rule or the other or dealing with incompetent bureaucracy or corruption," said Indian-American academic Vivek Wadhwa.
</p>

<p>
	 
</p>

<p>
	"Those skills are very useful when you're innovating in Silicon Valley, because you have to constantly challenge authority."
</p>

<p>
	 
</p>

<p>
	And they are valuable: ride-hailing giant Uber this month offered IIT Bombay students first-year packages of $274,000 for jobs in the United States.
</p>

<p>
	 
</p>

<p style="text-align:center;">
	<img alt="shivani-nandgaonkar-wa.jpg" class="ipsImage" data-ratio="73.47" height="477" width="720" src="https://scx1.b-cdn.net/csz/news/800a/2021/shivani-nandgaonkar-wa.jpg" />
</p>

<p style="text-align:center;">
	<span style="font-size:12px;"><em>Shivani Nandgaonkar wants to follow in the footsteps of IIT grads who have gone on to become CEOs at some of the world's biggest tech firms.</em></span>
</p>

<p style="text-align:center;">
	 
</p>

<p>
	The contest for such prizes begins early in a country of more than 1.3 billion people with a longstanding focus on education.
</p>

<p>
	 
</p>

<p>
	The IITs are seen as India's top universities, and more than one million pupils apply each year for just 16,000 places.
</p>

<p>
	 
</p>

<p>
	For one-and-a-half years, Nandgaonkar studied up to 14 hours a day, seven days a week. Some other students started preparations at just 14 or 15, she added.
</p>

<p>
	 
</p>

<p>
	"Imagine having an entrance which is 10x more difficult than MIT and Harvard. That's what the IITs are," Wadhwa said. "So it's the creme de la creme of the country."
</p>

<p>
	 
</p>

<p>
	<strong>India's biggest export?</strong>
</p>

<p>
	 
</p>

<p>
	The IIT network was established in 1950 by the country's first prime minister Jawaharlal Nehru, who envisaged a pool of highly trained science and engineering graduates to help build India after the end of British rule in 1947.
</p>

<p>
	 
</p>

<p>
	But the supply of engineers was not matched by sufficient domestic demand, so graduates looked further afield, particularly in the United States where there was hunger for highly skilled workers as the digital revolution took off.
</p>

<p>
	 
</p>

<p style="text-align:center;">
	<img alt="the-admissions-process.jpg" class="ipsImage" data-ratio="73.89" height="478" width="720" src="https://scx1.b-cdn.net/csz/news/800a/2021/the-admissions-process.jpg" />
</p>

<p style="text-align:center;">
	<span style="font-size:12px;"><em>The admissions process for IITs is highly competitive.</em></span>
</p>

<p style="text-align:center;">
	 
</p>

<p>
	"In the '60s '70s, and '80s, even into the '90s, Indian industry was not yet at the advanced (stages) and... a lot of those who wanted to do cutting-edge technology felt the need to go abroad," IIT Bombay Deputy Director S. Sudarshan said.
</p>

<p>
	 
</p>

<p>
	Agrawal, Pichai and Nadella spent a decade or more working their way through the ranks of their respective companies, building up insider knowledge while gaining the trust of the firms' American founders.
</p>

<p>
	 
</p>

<p>
	And for years, more than half the applicants for US H1-B skilled immigrant visas have been from India, and mostly from the tech sector.
</p>

<p>
	 
</p>

<p>
	In contrast, engineers from even more populous China had the option of finding jobs at home or returning after completing their US postgrads as their domestic economy boomed, said Johns Hopkins University professor Devesh Kapur, an IIT graduate himself.
</p>

<p>
	 
</p>

<p>
	The phenomenon may wane in time as India's own tech sector thrives, offering the country's best and brightest minds greater domestic opportunities, but for Nandgaonkar, becoming a tech boss like Agrawal or Pichai is not a far-fetched idea.
</p>

<p>
	 
</p>

<p>
	"Why not?" she said, "Dream big!"
</p>

<p>
	 
</p>

<p>
	<strong><a href="https://techxplore.com/news/2021-12-global-tech-indian-talent.html" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3602</guid><pubDate>Thu, 09 Dec 2021 12:34:15 +0000</pubDate></item><item><title>Omicron weakens vaccine protection, but boosters revive defenses, early data finds</title><link>https://nsaneforums.com/news/general-news/omicron-weakens-vaccine-protection-but-boosters-revive-defenses-early-data-finds-r3594/</link><description><![CDATA[<div data-page="1">
	<div>
		<header>
			<h2 itemprop="description">
				Omicron is "a tractable problem with the tools we have."
			</h2>
		</header>

		<section>
			<div itemprop="articleBody">
				<p>
					The first batch of preliminary laboratory data on the omicron coronavirus variant has come out, and the results are largely what health experts have anticipated: protective antibodies from two doses of the Pfizer-BioNTech vaccine are considerably less effective at thwarting the new variant than older versions of the virus. However, antibody potency appears to rebound to fight omicron after a booster dose.
				</p>

				<p>
					 
				</p>

				<p>
					The results suggest that people who have only two doses of the mRNA vaccine may not be protected from infection but would likely remain protected from severe disease. The findings also suggest that maintaining high levels of protection against omicron will require a booster dose of the current vaccines—or even an omicron-specific shot in the future.
				</p>

				<p>
					 
				</p>

				<p>
					The top-line findings and conclusions come from three separate sets of laboratory experiments—all of which are extremely preliminary, involve small sample numbers, and have not been peer-reviewed or published in scientific journals.
				</p>

				<h2>
					Pfizer and BioNTech data
				</h2>

				<p>
					The freshest data comes from <a href="https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-provide-update-omicron-variant" rel="external nofollow">preliminary results reported online Wednesday morning by Pfizer and BioNTech</a>. The companies conducted laboratory experiments that pitted antibodies from the blood serum of vaccinated people against a pseudovirus engineered to mimic the omicron variant. The experiments specifically measured the activity of neutralizing antibodies, which are a subset of antibodies that can bind to SARS-CoV-2 virus particles in such a way that the virus is prevented from entering human cells. Neutralizing antibodies are the most potent at preventing infection, but the immune system also produces a diverse array of other antibodies that can help fight an infection. Additionally, the immune system has protective cell-based responses that are not captured in these types of laboratory experiments.
				</p>

				<p>
					 
				</p>

				<p>
					In experiments using the blood sera of people fully vaccinated with the Pfizer-BioNTech vaccine (two doses), neutralizing antibody levels fell 25-fold against the omicron-mimicking pseudovirus compared with levels seen against a pseudovirus mimicking an older version of the virus. But when the companies looked at blood sera from fully vaccinated people one month after they received a vaccine booster shot (three doses), neutralizing antibody levels rebounded 25-fold against omicron, making them comparable to neutralizing antibody levels seen against older versions of the virus.
				</p>

				<p>
					 
				</p>

				<p>
					"Although two doses of the vaccine may still offer protection against severe disease caused by the omicron strain, it’s clear from these preliminary data that protection is improved with a third dose of our vaccine," Pfizer CEO Albert Bourla said in a statement. "Ensuring as many people as possible are fully vaccinated with the first two-dose series and a booster remains the best course of action to prevent the spread of COVID-19."
				</p>

				<p>
					 
				</p>

				<p>
					The companies also reported that they are still working on an omicron-specific vaccine dose in case it is needed. The timeline for the first batches to be available is still within 100 days from now, the companies said.
				</p>
			</div>
		</section>
	</div>
</div>

<div data-page="2">
	<div>
		<section>
			<div itemprop="articleBody">
				<h2>
					Data from South Africa and Germany
				</h2>

				<p>
					Pfizer and BioNTech's preliminary data on neutralizing antibodies is mostly echoed by a small preliminary study posted online Tuesday by researchers at the Africa Health Research Institute in South Africa. The researchers, led by virologist <a href="https://twitter.com/sigallab/status/1468325159501287434" rel="external nofollow">Alex Sigal</a>, looked at neutralizing antibody levels in six people with two doses of the Pfizer-BioNTech vaccine and six additional people with two Pfizer-BioNTech doses plus an earlier case of COVID-19 prior to omicron's rise. Unlike Pfizer and BioNTech, the researchers in South Africa used a live omicron virus rather than a pseudovirus in their experiments.
				</p>

				<p>
					 
				</p>

				<p>
					Among samples from all 12 people, neutralizing antibody levels against omicron fell 41-fold compared with levels seen against an earlier version of the virus. However, the six people who had been vaccinated and previously infected generally had higher levels of antibodies. Sigal noted on Twitter that the fold change among antibody levels will likely change as samples from more people are tested. Antibody levels vary from person to person and depend on a variety of factors such as immune status and time past vaccination or infection, among other things.
				</p>

				<p>
					 
				</p>

				<p>
					Overall, Sigal was optimistic about the findings, noting that—as expected—omicron lowers the effectiveness of vaccines, but not completely. That is, some vaccine-derived defenses can fight omicron, and those defenses can be amplified and elevated by booster doses of current vaccines. The data "means <a href="https://twitter.com/sigallab/status/1468346776583344132" rel="external nofollow">it's a tractable problem with the tools we got</a>," Sigal wrote on Twitter.
				</p>

				<p>
					 
				</p>

				<p>
					Lastly, the findings are further supported by preliminary data <a href="https://twitter.com/CiesekSandra/status/1468465347519041539" rel="external nofollow">posted on Twitter Wednesday</a> by researchers in Germany who found a drop in neutralizing antibody levels against omicron compared with delta in people fully vaccinated with various two-dose vaccine regimens.
				</p>

				<p>
					 
				</p>

				<p>
					Together, the experiments all point to a hit to vaccine protection but the preservation of lingering defenses that are demonstrably boostable to fight omicron. And as mentioned above, these experiments only assess one aspect of protection, neutralizing antibodies. Other antibodies and cell-based protections help prevent infection and disease. Moreover, cell-based protections are far less likely to be thwarted by omicron. The variant uses its many mutations to evade potent antibodies, but those mutations don't affect how well cells, namely certain T cells, respond to the virus. We ultimately won't know omicron's true impact on vaccine effectiveness until there is real-world data from large numbers of vaccinated people.
				</p>
			</div>
		</section>
	</div>
</div>

<p>
	 
</p>

<p>
	 
</p>

<p>
	<a href="https://arstechnica.com/science/2021/12/early-omicron-data-finds-vaccine-protection-stumbles-but-recovers-with-boosters/" rel="external nofollow">Omicron weakens vaccine protection, but boosters revive defenses, early data finds</a>
</p>
]]></description><guid isPermaLink="false">3594</guid><pubDate>Wed, 08 Dec 2021 22:21:43 +0000</pubDate></item><item><title>Nearly half of Australians are living with a chronic condition</title><link>https://nsaneforums.com/news/general-news/nearly-half-of-australians-are-living-with-a-chronic-condition-r3592/</link><description><![CDATA[<p>
	Chronic health conditions are the leading cause of poor health and mortality in Australia but they also have a major impact on other parts of people's lives. A new report from the Australian Institute of Health and Welfare (AIHW) brings together data on the wellbeing of working-age Australians with chronic conditions.
</p>

<p>
	 
</p>

<p>
	The report, Life and work experiences of Australians with chronic conditions, looks at how people with chronic conditions aged 15–64 were faring prior to 2020, providing baseline information for further research. It also takes an in-depth look at factors that were associated with poor health among mature working-age Australians (aged 45–64) living with chronic conditions.
</p>

<p>
	 
</p>

<p>
	"About 47% of Australians are estimated to have at least one chronic health condition, such as arthritis, asthma, cancer, cardiovascular diseases, and mental and behavioral conditions," said AIHW spokesperson Katherine Faulks.
</p>

<p>
	 
</p>

<p>
	Data from the Australian Bureau of Statistics National Health Survey show that in 2017–18, working-age Australians (15–64 years) living with chronic conditions when compared to those without chronic conditions were:
</p>

<p>
	 
</p>

<ul>
	<li>
		less likely to be employed either full-time or part-time, 71% compared with 80%
	</li>
</ul>

<p>
	 
</p>

<ul>
	<li>
		more likely to receive a government pension or allowance, 18% compared with 7%
	</li>
</ul>

<p>
	 
</p>

<ul>
	<li>
		more likely to live outside major city areas, 29% compared with 23%.
	</li>
</ul>

<p>
	<br />
	"More than a quarter (26%) of 45- to 64-year-olds with chronic conditions self-assessed their health as poor, compared to 16% of those aged 15–44," Ms. Faulks said.
</p>

<p>
	 
</p>

<p>
	"Among mature working-age Australians with chronic conditions, individual-based measures of socioeconomic position such as family composition of household, home ownership, and education were found to be important factors in their likelihood of reporting poor self-assessed health.
</p>

<p>
	 
</p>

<p>
	"Mature working-age Australians with chronic conditions were more likely to report poor health if they had any of the following characteristics: three or more types of chronic conditions; any activity limitations or a disability; were male; were renters; were living alone; had no tertiary qualifications."
</p>

<p>
	 
</p>

<p>
	The pandemic has affected the lives of all Australians but many people with chronic conditions have faced some particular challenges. For example, people with chronic conditions are at greater risk of severe illness from COVID-19 than those without chronic conditions.
</p>

<p>
	 
</p>

<p>
	As Australians with chronic conditions are more likely to live on their own, many may have been at increased risk of experiencing social isolation and loneliness when lockdowns and other measures which limited social interaction were in place. More research is needed to understand the impact of the COVID-19 pandemic on labor force participation among mature working-age people with chronic conditions.
</p>

<p>
	 
</p>

<p>
	Future research into the experiences of working-age Australians with chronic conditions could also look at specific groups, such as Aboriginal and Torres Strait Islander people with chronic conditions.
</p>

<p>
	 
</p>

<p>
	<strong><a href="https://medicalxpress.com/news/2021-12-australians-chronic-condition.html" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3592</guid><pubDate>Wed, 08 Dec 2021 15:28:44 +0000</pubDate></item><item><title>Physics Nobel belies Italy's scientific brain drain</title><link>https://nsaneforums.com/news/general-news/physics-nobel-belies-italys-scientific-brain-drain-r3562/</link><description><![CDATA[<p>
	Italian physicist Giorgio Parisi will receive a shared Nobel prize at a ceremony Monday, but behind the celebrations is consternation at the brain-drain that for years has seen many young scientists leave to work abroad.
</p>

<p>
	 
</p>

<p>
	Some 14,000 Italian researchers quit the country between 2009 and 2015, according to Italy's national statistics agency Istat—a trend explained in large part by a lack of investment.
</p>

<p>
	 
</p>

<p>
	"Italy is not a welcoming country for researchers, whether Italian or foreign," Parisi said in October after being awarded the Nobel prize for his work on the interplay of disorder and fluctuations in physical systems.
</p>

<p>
	 
</p>

<p>
	"Research is underfunded and the situation has worsened over the past 10-15 years."
</p>

<p>
	 
</p>

<p>
	Government funding fell from 9.9 billion euros ($11.2 billion) in 2007 to 8.3 billion in 2015—the latest figures available—while in 2019, research spending in the eurozone's third largest economy was significantly below the EU average.
</p>

<p>
	 
</p>

<p>
	As well as Parisi, Italy has produced some top scientists in recent decades, notably Carlo Rubbia, the CERN physicist who won a Nobel in 1984, and neuroembryologist Rita Levi-Montalcini, who won in 1986.
</p>

<p>
	 
</p>

<p>
	But commentators note that research budgets were slashed after the 2008 financial crisis, while Italy's notorious bureaucracy also plays a role in sending young talent abroad.
</p>

<p>
	 
</p>

<p>
	"In Italy, unfortunately, there are big obstacles to getting a university job," said Eleonora D'Elia, a 35-year-old biologist from Rome, who has been teaching for the past four years at Imperial College London.
</p>

<p>
	 
</p>

<p>
	She cited "a lack of funding, and jobs available, the contacts needed and a highly complex system based on the number of articles published".
</p>

<p>
	 
</p>

<p>
	<strong>Like a vegetable garden</strong>
</p>

<p>
	 
</p>

<p>
	The scale of the problem was confirmed by Roberto Antonelli, head of the prestigious Lincean Academy in Rome, who told AFP there had been "an enormous reduction in funds for universities and Italian research facilities".
</p>

<p>
	 
</p>

<p>
	This was accompanied by "a reduction in the quality of positions available for young people compared to other countries".
</p>

<p>
	 
</p>

<p>
	The number of professors and of long-term contracts at universities has fallen from 60,882 in 2009 to 48,878 in 2016—a drop of almost 20 percent.
</p>

<p>
	 
</p>

<p>
	In London, d'Elia told AFP, there is "more support in terms of salary and research budget", whereas in Italy, where she hopes one day to return to be with her family and friends, she "would have to constantly fight to get that".
</p>

<p>
	 
</p>

<p>
	The Italian government has vowed to use some of the massive post-pandemic recovery funds it expects to receive from the European Union between now and 2026 to help boost home-grown research.
</p>

<p>
	 
</p>

<p>
	Research Minister Cristina Messa in October promised six billion euros in funding for 60 projects.
</p>

<p>
	 
</p>

<p>
	<strong>'Like a vegetable garden'</strong>
</p>

<p>
	 
</p>

<p>
	Antonelli welcomed the funds, but warned: "The problem is the continuity of funding... what will happen after 2026?"
</p>

<p>
	 
</p>

<p>
	He said research must be measured in percentage of GDP, which ranges from "the highest such as in Finland, Japan and South Korea, to the lowest among developed countries such as Italy, which do not invest comparable funds when compared to neighbours such as Germany or France".
</p>

<p>
	 
</p>

<p>
	Italy spent just 1.45 percent of gross domestic product (GDP) on research in 2019, below the EU average of 2.19 percent and Germany's 3.17 percent, according to data from European agency Eurostat.
</p>

<p>
	 
</p>

<p>
	Parisi has also emphasised the importance of a long-term view.
</p>

<p>
	 
</p>

<p>
	"Research is like a vegetable garden, if you think you can water it every fortnight, things will go wrong," he said.
</p>

<p>
	 
</p>

<p>
	<strong><a href="https://phys.org/news/2021-12-physics-nobel-belies-italy-scientific.html" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3562</guid><pubDate>Sun, 05 Dec 2021 14:00:12 +0000</pubDate></item><item><title>So metal: Newly discovered exoplanet is likely over 80 percent iron</title><link>https://nsaneforums.com/news/general-news/so-metal-newly-discovered-exoplanet-is-likely-over-80-percent-iron-r3547/</link><description><![CDATA[<header>
	<h2 itemprop="description">
		It looks a lot like a hot version of the innermost planet in our Solar System.
	</h2>

	<p>
		<img alt="tess_6-800x476.jpg" class="ipsImage" data-ratio="65.97" height="428" width="720" src="https://cdn.arstechnica.net/wp-content/uploads/2018/09/tess_6-800x476.jpg">
	</p>
</header>

<section>
	<div itemprop="articleBody">
		<figure>
			<figcaption>
				<div>
					The TESS planet-finding observatory.
				</div>

				<div>
					<a href="https://www.nasa.gov/mediacast/gravity-assist-tess-exoplanets-with-martin-still" rel="external nofollow">NASA</a>
				</div>
			</figcaption>
		</figure>

		<p>
			For centuries, scientists only had a limited number of examples to look at when it came to understanding the formation of planets. As we've discovered ever-increasing numbers of worlds, however, we've found many that look like nothing that we have in our Solar System: hot gas giants, super-Earths, mini-Neptunes, and more. So, it can be a relief to find something that looks like a familiar planet, since it indicates the processes that formed the Solar System may not be unusual.
		</p>

		<p>
			 
		</p>

		<p>
			A new discovery definitely falls into that category, as researchers have announced finding what appears to be an extremely iron-rich planet that, at least composition-wise, is very similar to Mercury. The difference is that it's nearly on top of its star and is probably hot enough that any iron on the surface could potentially be molten.
		</p>

		<h2>
			A very short year
		</h2>

		<p>
			The new planet was found orbiting a red dwarf star named GJ 367 that's about 30 light years from Earth. Red dwarfs are small, dim stars, which makes identifying planets around them easier. A planet that orbits between a red dwarf and Earth will block out proportionally more of the star's light. And, because the star is low mass, a planet's gravity will cause it to shift further when it orbits, creating larger Doppler shifts in the light originating from the star.
		</p>

		<p>
			 
		</p>

		<p>
			The new planet, GJ 367b, turned up in data from NASA's Transiting Exoplanets Survey Satellite (TESS) mission. TESS watches for drops in starlight caused by an orbiting planet, and it does so at an impressive clip—the data used here included a new image every two minutes for a total of two weeks. That's more than enough to pick out the signal caused by GJ 367b, which completes a trip around its star in only a third of a day.
		</p>

		<p>
			 
		</p>

		<p>
			Detection by this method makes GJ 367b an exoplanet candidate; to confirm its existence, the research team turned to an Earth-based telescope, which watched for the Doppler shifts in the star's light caused by the planet's orbit. This confirmed the planet's existence, as the third-of-a-day signal was present (as was a roughly 45-day signal caused by the star's rotation.)
		</p>

		<p>
			 
		</p>

		<p>
			The planet itself is small, with a radius that's only three-quarters that of Earth's. But it's relatively hefty, with a mass that's over half that of Earth's. That leads to a density that's a bit over eight grams per cubic centimeter—which is actually heavier than that of iron.
		</p>

		<h2>
			Hellish conditions
		</h2>

		<p>
			GJ 367b is close enough to be tidally locked with its host star, meaning it rotates once per orbit, keeping a single side facing the star the entire time. And it is very close to that star. This leads to an estimated surface temperature of 1,745 Kelvin—very close to the melting point of iron. Of course, the outer crust is likely to be rocky. Or would be rocky if it weren't for the fact that many silicon-rich rocks melt at similar temperatures as well.
		</p>

		<p>
			 
		</p>

		<p>
			Obviously, anything that resembles an atmosphere as we're familiar with it would have been heated off long ago. But there's a chance that some of the molten rock and metals would vaporize and create a bit of a local atmosphere on the star-facing side. Obviously, the far side of the planet would be cooler, and anything in vapor form will likely end up back on the planet very quickly.
		</p>

		<p>
			 
		</p>

		<p>
			The research team fed the stats to an AI trained on other planets, and the AI predicted that GJ 367b has a structure much like Mercury's: a large metallic core taking up much of the interior of the planet, extending over 85 percent of the way to the surface. The rest would be silicate rocks. Which is not unreasonable, other than the fact that the density of GJ 367b is 1.5 times that of Mercury's. So, there must be some significant differences, as well.
		</p>

		<p>
			 
		</p>

		<p>
			In any case, we have some idea of how Mercury got to be so iron-rich—it's a product of collisions that stripped off some rocky material. But we don't understand how anything Mercury-sized could have formed in such close proximity to a star. So, while there is some comforting familiarity here, there are definitely limits to it.
		</p>

		<p>
			 
		</p>

		<p>
			Science, 2021. DOI: <a href="http://dx.doi.org/10.1126/science.aay3253" rel="external nofollow">10.1126/science.aay3253</a>  (<a href="http://arstechnica.com/science/news/2010/03/dois-and-their-discontents-1.ars" rel="external nofollow">About DOIs</a>).
		</p>
	</div>
</section>

<p>
	 
</p>

<p>
	 
</p>

<p>
	<a href="https://arstechnica.com/science/2021/12/researchers-spot-a-mercury-like-planet-orbiting-a-star-30-light-years-away/" rel="external nofollow">So metal: Newly discovered exoplanet is likely over 80 percent iron</a>
</p>
]]></description><guid isPermaLink="false">3547</guid><pubDate>Fri, 03 Dec 2021 22:27:35 +0000</pubDate></item><item><title>The omicron variant is a mystery. Here&#x2019;s how science will solve it</title><link>https://nsaneforums.com/news/general-news/the-omicron-variant-is-a-mystery-here%E2%80%99s-how-science-will-solve-it-r3538/</link><description><![CDATA[<div data-page="1">
	<div>
		<header>
			<h2 itemprop="description">
				So far, panic about the new Covid variant has outpaced actual information.
			</h2>
		</header>

		<section>
			<div itemprop="articleBody">
				<p>
					Starting last Friday, the race was on—between a virus and information about it. And for a while, the information moved faster, even though there was hardly any of it.
				</p>

				<p>
					 
				</p>

				<p>
					Scientists in South Africa identified a new variant of the virus that causes <a href="https://arstechnica.com/tag/covid-19/" rel="external nofollow">COVID-19</a>—within days the World Health Organization gave it the spy-sci-fi name omicron—and because of the abundant smorgasbord of mutations in its spike protein, the nanomechanical tentacle that attaches and cracks into cells, science alarms started going off.
				</p>

				<p>
					 
				</p>

				<p>
					But to be clear, they were the "We should check this out" alarms, not the "Everybody lose their effing minds" alarms. Apparently they sound alike, though. Panic took flight as scientists identified omicron in <a href="https://www.cnn.com/2021/11/29/world/covid-omicron-variant-countries-list-cmd-intl/index.html" rel="external nofollow">18 countries</a>, triggering <a href="https://www.nbcnews.com/news/all/map-more-30-countries-institute-omicron-related-travel-restrictions-n1285095" rel="external nofollow">travel bans</a>, <a href="https://www.cnn.com/travel/article/coronavirus-omicron-variant-travel-restrictions/index.html" rel="external nofollow">border closures</a>, <a href="https://www.washingtonpost.com/business/2021/11/30/stock-market-omicron-uncertainty/" rel="external nofollow">stock market crashes</a>, and, in the United States, holiday weekend worries that the world was headed back to March of 2020. Researchers in South Africa and Botswana have found the most cases thus far, though that may be an artifact of looking for them; on Tuesday, Dutch authorities announced that the earliest case they can identify is <a href="https://www.cbsnews.com/news/omicron-variant-covid-in-europe-netherlands-before-alert-raised/?ftag=CNM-00-10aab7e&amp;linkId=142329193" rel="external nofollow">11 days old</a>, predating omicron's identification in South Africa.
				</p>

				<p>
					 
				</p>

				<p>
					That means the omicron variant is widespread and mysterious—a palimpsest wrapped in a hologram draped in a Rorschach test—because nobody knows nothin' yet. Public health authorities can't yet say whether it is more virulent or more transmissible than delta, which since last summer has crowded out most other variants of SARS-CoV-2. So panic; or don't. That's on you. Because now scientists have to work the problem.
				</p>

				<p>
					 
				</p>

				<p>
					The things scientists don't know, but need to: how efficiently does omicron move from person to person? Can it evade the immunity conferred by prior infection, or by vaccines? Does it cause more serious illness? "We need multiple types of data," says Angela Rasmussen, a coronavirologist at the Vaccine and Infectious Disease Organization-International Vaccine Centre in Saskatchewan, Canada. That means getting genomic and epidemiological data, understanding the variant's immunological differences, and collecting stats on breakthrough infections and hospitalizations.
				</p>

				<p>
					 
				</p>

				<p>
					That's all going to be complicated, because a crucial piece of information is missing: How long omicron has been spreading around the world. That new Dutch data suggests it has been longer than health planners first hoped. Whether this is the beginning of a wave—or the middle or end of one that no one noticed—is key. "It appears to have been caught at the beginning of an upswing, at a time where everybody has been focused on delta," says John Connor, a microbiologist at Boston University and investigator at its National Emerging Infectious Diseases Laboratories. "The nice part about having that information early is that the rest of the world can start examining all the questions that are raised by a new variant: Do our diagnostics still work? Does it look like the immune response generated by vaccines can still neutralize this virus?"
				</p>

				<p>
					 
				</p>

				<p>
					If this is just the beginning, let's say, then everyone with omicron might still be one tight-knit group, demographically or biologically speaking. That might make the variant seem more dangerous—faster-moving or making people sicker—if that group was for some reason more vulnerable than the general population. Or the opposite might be true. To figure that out, disease dynamics researchers might do "forensic accounting" to see how prior waves like delta behaved, and compare that to what's happening with omicron. That might say something about whether they're under- or overestimated how bad an omicron wave could be. "If I were to have assessed delta using only the time period that corresponds to about now, how wrong would I have been?" says Matthew Ferrari, director of the Center for Infectious Disease Dynamics at Penn State University.
				</p>

				<p>
					 
				</p>

				<p>
					In short: based on early data, scientists knew very little about delta. Now they know it inside out. They'll need the same patience to understand omicron. As a first step, more details of the variant's genetic structure, initially generated by scientists in South Africa, might help with early ideas about the variant's behavior as it spreads. "One can then infer from the genetics as to how this virus may escape antibody neutralization, whether it will escape vaccines or not," says Deenan Pillay, a virologist at University College London. But that's all inference, he adds: "One can never know, but one can make a calculated assessment based on what we know about the genetics of other variants."
				</p>
			</div>
		</section>
	</div>

	<div>
		 
	</div>
</div>

<div data-page="2">
	<div>
		<section>
			<div itemprop="articleBody">
				<p>
					The next answers will build on existing work—in fact, on the work that makes people so worried about omicron. Scientists have already taken modified versions of the spike protein and stuck it onto a virus that doesn't hurt people (usually something like Vesicular Stomatitis Virus, or VSV, denuded into a "pseudovirus"), then combined it with sera—basically the immunological parts of blood—from different kinds of people. Typically, that's those who've had COVID and recovered, or been vaccinated, or who've been treated with monoclonal antibodies. Then they check for "binding affinity," basically how much of an immune response those different sera mount against the protein, and that tells you how good the immune system is at beating the changes in the spike. "You find the titer or dilution that reduces the number of plaques that the virus or pseudovirus makes on the cells by 50 percent," says A. Marm Kilpatrick, an infectious disease researcher at UC Santa Cruz. "Usually one compares neutralizing titers of a new variant to a previous variant."
				</p>

				<p>
					 
				</p>

				<p>
					Researchers have these numbers for other COVID variants, including delta, alpha, and even the original one found in Wuhan. "What's especially interesting about omicron is that there are so many changes relative to what we've seen in the wild type and delta, the primary variants we've had so far," Ferrari says. "It's so many differences that we now have to worry about how those differences interact with each other."
				</p>

				<p>
					 
				</p>

				<p>
					The next step will be to do those same assays, virus versus immunity, with omicron itself. "That's taking the real virus," Ferrari says. "We can do them relatively quickly, but they have to be done in specialized settings—biosafety level 3." That means laboratories set up for dangerous respiratory pathogens, with air locks and everyone wearing protective equipment and respirators. Ferrari says those results are anywhere from one to two weeks away; Kilpatrick says they might come even sooner.
				</p>

				<p>
					 
				</p>

				<p>
					A problem, of course, is that this is still just bench-based information. "What we see in a lab is much simpler than what happens in real life; our real immune systems are obviously much more complex," says Emma Hodcroft, an evolutionary geneticist at the University of Bern. "And so that means that we cannot perfectly predict, just from looking at the sequences, how much immune evasion this variant might have, or how much more transmissible it is. We really need to wait for more data to see that."
				</p>

				<p>
					 
				</p>

				<p>
					To gain a real-world picture of how much risk omicron poses, it will be critical to match any sequences to clinical data: who got sick, how sick they got, their demographics, and whether they'd ever been infected or vaccinated before omicron got to them. "It's really important to note that we don't necessarily really have any indication from the sequence about whether the variant is more or less clinically dangerous," Hodcroft says. "It's also really important that the first people with this with omicron were not identified with this very long ago. And oftentimes, the more severe outcomes, we don't see them for a few weeks."
				</p>

				<p>
					 
				</p>

				<p>
					One thing that is clear, though, is that it's a mistake to blame South Africa for the variant's emergence. Researchers there are just very good at spotting variants and were transparent enough to warn the world. Still, omicron's numbers there may provide important clues to its clinical course. South Africa is a youthful country; 37 percent of its population is <a href="https://www.statista.com/statistics/1116077/total-population-of-south-africa-by-age-group/" rel="external nofollow">under 20</a> years old. (In the US, for comparison, 22 percent of the population is <a href="https://www.census.gov/quickfacts/fact/table/US/PST045219" rel="external nofollow">younger than 19</a>.) Because younger people tend to fight COVID better, that may have skewed initial impressions that omicron <a href="https://www.statnews.com/2021/11/30/doctors-hope-omicron-causes-milder-cases-of-covid-but-its-still-too-early-to-say/" rel="external nofollow">causes mild illness</a>. "One of the key things we need to do is really keep an eye on what's going on with the spread of the variant in other populations, particularly looking at how much infection there is in South Africa and what that means for hospitalizations," says Lawrence Young, a virologist at the University of Warwick Medical School. "If we're going to see any results around the ability of omicron to cause more severe disease or otherwise, it will be in South Africa."
				</p>

				<p>
					 
				</p>

				<p>
					A further confounder is that HIV-AIDS remains widespread across sub-Saharan Africa, where many infected people haven't had access to antiretroviral medications available in the Global North. That could mean disease synergy: someone whose immune system has been undermined by that disease could have been the <a href="https://www.wired.com/story/protecting-the-immune-compromised-keeps-everyone-safe/" rel="external nofollow">incubator</a> for the variant to <a href="https://www.wired.com/story/the-raging-evolutionary-war-between-humans-and-covid-19/" rel="external nofollow">develop its mutations</a>—as happened last year with <a href="https://www.nature.com/articles/s41586-021-03291-y" rel="external nofollow">an immunocompromised patient in the United Kingdom</a>. "In somebody with a strong immune system, the virus will only be able to evolve so much before that person's immune system sort of squashes the replication. But we know in immunocompromised individuals, the virus just runs amok," says Anna Bershteyn, an assistant professor and co-lead of the COVID modeling team at NYU Grossman School of Medicine. "There's a little bit of comfort there, because the evolutionary pressure of a virus running amok inside one body of an immunocompromised person is not necessarily going to push it evolutionarily into something that makes it really horrible for humanity at large."
				</p>

				<p>
					 
				</p>

				<p>
					Finding out what omicron does in humans, rather than petri dishes, will take a long time. Even the seemingly basic question of whether omicron causes more severe infections won't be easy to figure out. Researchers will use hospital data, so they have to wait until enough people actually get sick enough to need a doctor. Ideally, the people they study will all be unvaccinated, with no previous infection. "I'm not sure there are enough people left in South Africa that weren't exposed before for this data to be possible there," Kilpatrick says. If it isn't, he says, the alternative would be to study how effective the vaccine is at keeping people from illness so severe they have to be hospitalized.
				</p>
			</div>
		</section>
	</div>
</div>

<div>
	 
</div>

<div data-page="3">
	<div>
		<section>
			<div itemprop="articleBody">
				<p>
					Researchers will also try to compare the rate at which vaccinated people get breakthrough infections versus the infection rate among the unvaccinated—though the statistics get tricky. These would be observational studies, and they risk the potential of bias in which groups they include and how they measure them. For example, the difference between the two groups could be a function of which populations have access to hospitals and medical care. Kilpatrick says these studies could take four to six weeks.
				</p>

				<p>
					 
				</p>

				<p>
					Meanwhile, the proxy for virology is epidemiology. You have to measure how much omicron is out there relative to other variants. Researchers around the world will test new cases of COVID to see which variant people have, and whether omicron's numbers are growing faster than, say, delta's—to figure out if the new variant transmits from person to person more easily, or if it slides past people's immune systems better. "If we see fast replacement, that's indicative of either fast transmission, or it could be indicative of immune evasion," Ferrari says. "The two things are confounded right now. If we see a replacement of delta by omicron, we won't necessarily know immediately if that's because of increased transmissibility or decreased immune protection."
				</p>

				<p>
					 
				</p>

				<p>
					And after that—or amid all that—the boots-on-the-ground epidemiology of household transmission tracking will also start. That'll help give a better estimate of transmissibility, of whether omicron actually spreads faster and more aggressively than other variants. "Secondary attack rate, the number of people you spread the virus to, is a much more explicit measure of transmissibility, but it's a longer, slower process," Ferrari says.
				</p>

				<p>
					 
				</p>

				<p>
					While some researchers are figuring out what they need to know next, others are hoping to unwind the unhelpful things that have already happened. If sub-Saharan Africa wasn't actually the home of the variant—or even if it was, but the variant has long escaped—there's no scientific rationale for interdictions against travel. The bans "make no sense and send the wrong message. They should be reversed immediately," says Madhukar Pai, a physician, epidemiologist, and associate director of McGill University's International TB Centre. "Vaccine mandates and pre/post departure rapid testing can be used to protect travelers and borders."
				</p>

				<p>
					 
				</p>

				<p>
					Meanwhile, travel interdictions are preventing research from moving forward. For one thing, they're keeping people from getting isolated samples of the omicron variant. "The speed at which we get laboratory data is going to depend on how quickly we get access to virus isolates," Rasmussen says. "The travel bans have made it more challenging to get materials to and from southern Africa, so they are actively hindering research efforts."
				</p>

				<p>
					 
				</p>

				<p>
					In this view, reversing the bans would be the first step to ameliorating the North-South inequity that probably helped omicron emerge by throttling the availability of vaccines in the Global South. "I would love to see a powerful, concerted, global push for vaccinating the world," Pai says. Richer, whiter countries would have to <a href="https://www.wired.com/story/the-pandemic-cant-end-while-wealthy-nations-hoard-shots/" rel="external nofollow">stop hoarding vaccines</a>, increase donations to the international vaccine-providing organization Covax, and pressure pharmaceutical companies to waive patent rights and transfer their technology to generic drug makers to increase production.
				</p>

				<p>
					 
				</p>

				<p>
					Until all that happens: panic, right?
				</p>

				<p>
					 
				</p>

				<p>
					No—because no matter what all the mutations Frankenstein-stitched into the omicron spike protein add up to, masks still work, especially the higher-grade N95s or KN95s. The virus is still much less likely to transmit in well-ventilated indoor spaces or outdoors. Vaccinations almost certainly still convey some protection against the variant, and booster shots keep that protection from waning over time. All the interventions that worked last week still work this week and will keep working for the "<a href="https://www.cnbc.com/2021/11/28/fauci-says-us-should-prepare-to-do-anything-to-fight-omicron-variant.html" rel="external nofollow">two weeks</a>" that US National Institute of Allergy and Infectious Disease head Anthony Fauci said it would take to get better data. "Regardless of how little we know about omicron," says Beth Linas, a research epidemiologist at the independent R&amp;D institute RTI International, "we know the best way to protect yourself and others now is to get vaccinated and boosted."
				</p>

				<p>
					 
				</p>

				<p>
					That's good advice, even putting omicron aside. Its arrival doesn't mean delta has departed. Around the world, that wave is still propagating. Austria is currently under <a href="https://www.wired.co.uk/article/lockdown-austria-covid-19" rel="external nofollow">a nationwide lockdown</a>. The Netherlands is effectively closed from 5 pm to 5 am. Half-a-million people around the world get sick every week, and about 7,000 die. "Omicron is a spark that should not distract us from the fact that we're already in a burning building," Hodcroft says. People are still getting sick and dying from the old variant. There is still work to be done.
				</p>

				<p>
					 
				</p>

				<p>
					<a href="https://www.wired.co.uk/profile/adam-rogers" rel="external nofollow" target="_blank">Adam Rogers</a>, <a href="https://www.wired.co.uk/profile/grace-browne" rel="external nofollow" target="_blank">Grace Browne</a>, and <a href="https://www.wired.co.uk/profile/maryn-mckenna" rel="external nofollow" target="_blank">Maryn McKenna</a> contributed to this story.
				</p>

				<p>
					 
				</p>

				<p>
					This story originally appeared on <a href="https://www.wired.co.uk/article/omicron-variant-facts" rel="external nofollow">Wired UK</a>.
				</p>
			</div>
		</section>
	</div>
</div>

<p>
	 
</p>

<p>
	 
</p>

<p>
	<a href="https://arstechnica.com/science/2021/12/the-omicron-variant-is-a-mystery-heres-how-science-will-solve-it/" rel="external nofollow">The omicron variant is a mystery. Here’s how science will solve it</a>
</p>
]]></description><guid isPermaLink="false">3538</guid><pubDate>Thu, 02 Dec 2021 23:13:04 +0000</pubDate></item><item><title>Getting software to &#x201C;hallucinate&#x201D; reasonable protein structures</title><link>https://nsaneforums.com/news/general-news/getting-software-to-%E2%80%9Challucinate%E2%80%9D-reasonable-protein-structures-r3537/</link><description><![CDATA[<div data-page="1">
	<div>
		<header>
			<h2 itemprop="description">
				Process resembles repeatedly asking the software "does this look like a protein?"
			</h2>

			<p>
				<img alt="Screen-Shot-2021-12-01-at-7.16.27-PM.jpg" class="ipsImage" data-ratio="63.47" height="417" width="720" src="https://cdn.arstechnica.net/wp-content/uploads/2021/12/Screen-Shot-2021-12-01-at-7.16.27-PM.jpg">
			</p>
		</header>

		<section>
			<div itemprop="articleBody">
				<figure>
					<figcaption>
						<div>
							Top row: the hallucination and actual structure. Bottom row: the two structures superimposed.
						</div>

						<div>
							Anishchenko et. al.
						</div>
					</figcaption>
				</figure>

				<p>
					Chemically, proteins are just a long string of amino acids. Their amazing properties come about because that chain can fold up into a complex, three-dimensional shape. So understanding the rules that govern this folding could not only give us insights into the proteins that life uses but could potentially help us design new proteins with novel chemical abilities.
				</p>

				<p>
					 
				</p>

				<p>
					There's been <a href="https://arstechnica.com/science/2021/07/google-turns-alphafold-loose-on-the-entire-human-genome/" rel="external nofollow">remarkable progress</a> on the <a href="https://arstechnica.com/science/2021/07/google-details-its-protein-folding-software-academics-offer-an-alternative/" rel="external nofollow">first half of that problem</a> recently: researchers have tuned AIs to sort through the evolutionary relationships among proteins and relate common features to structures. As of yet, however, those algorithms aren't any help for designing new proteins from scratch. But that may change, thanks to the methods described in a paper released on Wednesday.
				</p>

				<p>
					 
				</p>

				<p>
					In it, a large team of researchers describes what it terms protein "hallucinations." These are the products of a process that resembles a game of hotter/colder with an algorithm, starting with a random sequence of amino acids, making a change, and asking, "Does this look more or less like a structured protein?" Several of the results were tested and do, in fact, fold up like they were predicted to.
				</p>

				<h2>
					AI hallucinations
				</h2>

				<p>
					The odd terminology here can't be blamed on the authors of the new paper. Instead, the term "hallucination" was applied to <a href="https://ai.googleblog.com/2015/06/inceptionism-going-deeper-into-neural.html" rel="external nofollow">work done by Google's AI team</a>. That work involved starting with an image of random pixels and asking a neural network trained to recognize fruit, "How much does this look like a banana?" After some random tweaks, the question was asked again; any changes that increased the image's banana-like properties were retained, and the process repeated.
				</p>

				<p>
					 
				</p>

				<p>
					The end result clearly has banana-like aspects, but it looks more like a cubist and impressionist both had a go at the bananas before running a few random Photoshop filters. While the term isn't used in Google's blog post, others labeled the images "hallucinations."
				</p>

				<p>
					 
				</p>

				<p>
					<img alt="noise-to-banana.png" class="ipsImage" data-ratio="40.43" height="283" width="700" src="https://cdn.arstechnica.net/wp-content/uploads/2021/12/noise-to-banana.png">
				</p>

				<figure>
					<figcaption>
						<div>
							Random noise (left) gets converted to a banana-like hallucination (right) by repeated queries to a banana-recognition AI.
						</div>

						<div>
							<a href="https://ai.googleblog.com/2015/06/inceptionism-going-deeper-into-neural.html" rel="external nofollow">Google</a>
						</div>
					</figcaption>
				</figure>

				<p>
					The researchers thought that, if this works for AIs that handle image recognition, maybe it would also work with AIs that suggest 3D structures for proteins.
				</p>

				<p>
					 
				</p>

				<p>
					Those of you paying careful attention here may notice a problem, however. The biology-specific algorithms don't output a rating of whether something is structure-like; instead, they simply assume there's a structure and try to suggest what it is. So they're not inherently set up to do the sort of getting-hotter/getting-colder evaluation that's needed to create a hallucination.
				</p>

				<p>
					 
				</p>

				<p>
					The research team figured out a way around this, however. Unstructured proteins tend to spread out in space, with only a handful of neighboring amino acids interacting with each other. Highly structured proteins, by contrast, tend to be compact and fold so that amino acids in different parts of the chain can interact with each other. The algorithm they were using for structure prediction, <a href="https://yanglab.nankai.edu.cn/trRosetta/" rel="external nofollow">trRosetta</a>, outputs its predictions as the relative location of each amino acid in a 3D space. So, by using a measure of their spread, the authors were able to provide a sort of answer to the question "how structured does this look?"
				</p>

				<h2>
					Starting from random
				</h2>

				<p>
					To start their structural hallucinations, the researchers generated numerous proteins composed of 100 random amino acids and fed them to the trRosetta software. As expected, all of the proteins were unstructured at the start. Then, for each of the 100 sequences, an amino acid was chosen at random and changed to a different amino acid that was also chosen at random. trRosetta then ran a new analysis, and the results were compared; any change that made things look more structured was retained.
				</p>

				<p>
					 
				</p>

				<p>
					By about 20,000 repeats of this process, the compactness of the arrangement of the amino acids in these hallucinations were similar in nature to those of regular proteins. But, critically, the amino acid sequences didn't look like those of known proteins. The structures themselves didn't either. In the proteins used by life, there are often loops of poorly structured amino acids that perform key functions. But the hallucinations weren't selected for function; they were selected for compactness. So, those sorts of extended loops were not found in the hallucinations.
				</p>

				<p>
					 
				</p>

				<p>
					There are a couple of reasons to be skeptical that actual chains of amino acids would form these structures in the real world. trRosetta isn't the latest and greatest in structure-prediction software that's been making all the headlines. And trRosetta was trained to figure out structure in part by evaluating evolutionary relationships. These proteins are all brand new and have no evolutionary relatives. The process would only work if the neural network used in trRosetta had inferred principles of protein structure from those evolutionary relationships.
				</p>

				<p>
					 
				</p>

				<p>
					The only way to tell whether it worked is to make the actual proteins and see what they look like. So, the research team put together genes that encoded 129 hallucinatory proteins.
				</p>
			</div>
		</section>
	</div>
</div>

<div data-page="2">
	<div>
		<section>
			<div itemprop="articleBody">
				<h2>
					Out of computers, into E. coli
				</h2>

				<p>
					There seem to be two lessons to what the researchers saw when they made the proteins. The researchers could purify 27 of the proteins and find indications that they were likely forming the sorts of structures that the software had predicted. In a handful of cases, they obtained detailed structures, which showed the computer predictions were good in all cases. So, the software seems to be pretty good at getting us into the rough neighborhood of a real structure.
				</p>

				<p>
					 
				</p>

				<p>
					But the other thing that was clear was that a lot of the hallucinatory proteins formed aggregates by sticking together. The researchers suspect this was a product of the fact that many of the proteins that trRosetta was trained on are part of multiprotein complexes, and the basic principles of interactions among proteins work well when applied to new proteins. In other words, part of what the system recognized as "more like a structure" was actually a general feature of the proteins it was trained on.
				</p>

				<p>
					 
				</p>

				<p>
					The results as a whole, however, suggest that training AIs on proteins with known structure does, in fact, enable them to identify basic principles of the underlying biochemistry. And we can use that in reverse to come up with some novel structures, starting with nothing but a chain of random amino acids. So that's all good.
				</p>

				<p>
					 
				</p>

				<p>
					But there's not a clear link between this sort of structural information and any kind of function. So, while we can potentially compute a protein that will form a stable coil, we're still a long way off from getting that coil to, for example, break down a plastic. This work may be a critical first step toward that sort of capability. But there's no guarantee that it is at this point.
				</p>

				<p>
					 
				</p>

				<p>
					Nature, 2021. DOI: <a href="http://dx.doi.org/10.1038/s41586-021-04184-w" rel="external nofollow">10.1038/s41586-021-04184-w</a>  (<a href="http://arstechnica.com/science/news/2010/03/dois-and-their-discontents-1.ars" rel="external nofollow">About DOIs</a>).
				</p>
			</div>
		</section>
	</div>
</div>

<p>
	 
</p>

<p>
	 
</p>

<p>
	<a href="https://arstechnica.com/science/2021/12/getting-software-to-hallucinate-reasonable-protein-structures/" rel="external nofollow">Getting software to “hallucinate” reasonable protein structures</a>
</p>
]]></description><guid isPermaLink="false">3537</guid><pubDate>Thu, 02 Dec 2021 23:10:21 +0000</pubDate></item><item><title>Planetary scientists are starting to get stirred up by Starship&#x2019;s potential</title><link>https://nsaneforums.com/news/general-news/planetary-scientists-are-starting-to-get-stirred-up-by-starship%E2%80%99s-potential-r3534/</link><description><![CDATA[<div data-page="1">
	<div>
		<header>
			<h2 itemprop="description">
				"It could provide a revolutionary new way of exploring these worlds."
			</h2>

			<p>
				<img alt="48953947006_02a6ed229b_k-800x450.jpg" class="ipsImage" data-ratio="62.50" height="405" width="720" src="https://cdn.arstechnica.net/wp-content/uploads/2021/11/48953947006_02a6ed229b_k-800x450.jpg">
			</p>
		</header>

		<section>
			<div itemprop="articleBody">
				<figure>
					<figcaption>
						<div>
							A rendering of SpaceX's Starship traveling to the Saturn system.
						</div>

						<div>
							SpaceX
						</div>
					</figcaption>
				</figure>

				<p>
					Jennifer Heldmann stared at the computer screens on her desk, watching as a rocket's upper stage slammed into a crater near the South Pole of the Moon. In the name of science, a 2.3-ton chunk of steel struck the Moon with the force of 2 tons of TNT.
				</p>

				<p>
					 
				</p>

				<p>
					It was October 2009, and Heldmann tracked the impact from inside the Science Operations Center at NASA Ames in California. As a 33-year-old planetary scientist, she was working her first major mission for NASA by coordinating observations of the impact with ground-based telescopes.
				</p>

				<p>
					 
				</p>

				<p>
					NASA sought to "touch the ice" with the LCROSS mission. Although the Apollo landings in the 1960s and early 1970s had found a gray and barren world, scientists had since come to believe that pockets of ice were trapped below the rims of craters in permanent darkness at the poles, the remnants of billions of years of cometary impacts. Centaur's mission was to blast one of these craters and see if the scientists were right.
				</p>

				<p>
					 
				</p>

				<p>
					After poring over the data, NASA declared that it had indeed found water in the vapor plume kicked up by the Centaur impact, as well as material ejected by the blast.
				</p>

				<p>
					 
				</p>

				<p>
					For Heldmann, this was a pivotal moment in her career. The experience cemented her interest as a planetary scientist in following the water. "It is truly amazing how the results of that mission have been so profound," she said.
				</p>

				<p>
					 
				</p>

				<p>
					The discovery of water ice on the Moon highlighted an era in which planetary scientists were finding ice and water all over the Solar System—on the ice-encrusted moons of Europa and Enceladus, on and beneath the surface of Mars, and potentially in even more far-flung locations, such as the interior of Pluto or Neptune's largest moon, Triton. As they looked beyond Earth, scientists discovered, water was nearly everywhere.
				</p>

				<p>
					 
				</p>

				<p>
					These discoveries raised all manner of tantalizing prospects. Where there is water—or once was—life might have developed. Scientists were therefore no longer just looking for fossils in long-dry lake beds on Mars; they began seeking out living organisms in the large oceans of Europa, Enceladus, and elsewhere. For human exploration, too, the proliferation of water offered a great opportunity. Where there is water, there are the components for rocket fuel—liquid hydrogen and liquid oxygen.
				</p>

				<p>
					 
				</p>

				<p>
					In no small way, these discoveries have influenced the focus of NASA's science and human spaceflight programs. NASA has increasingly leveraged its annual planetary science budget, about $3 billion a year, to support missions that may find past or even present life on other worlds. And during the last four years, the space agency has been formulating a plan to send astronauts to the Moon, possibly to extract water there, as a precursor to sending humans to Mars.
				</p>

				<p>
					 
				</p>

				<p>
					<img alt="Perspective_view_of_Korolev_crater-1-980" class="ipsImage" data-ratio="75.10" height="404" width="720" src="https://cdn.arstechnica.net/wp-content/uploads/2021/11/Perspective_view_of_Korolev_crater-1-980x551.jpg">
				</p>

				<figure>
					<figcaption>
						<div>
							This image from the European Space Agency’s Mars Express shows Korolev crater, an 82-km-across feature found in the northern lowlands of Mars.
						</div>

						<div>
							ESA/DLR/FU Berlin
						</div>
					</figcaption>
				</figure>

				<p>
					For scientists, there are always more questions than answers. And there are always many more missions they want to fly than funds available to fly them. The ubiquity of water has only heightened scientists' desire to get robots out into the Solar System to definitively find ice deposits and subsurface oceans and to characterize them. Just as we're learning that the Solar System holds far more secrets than we might have imagined—which makes our inability to fly out there and unlock them especially frustrating.
				</p>

				<p>
					 
				</p>

				<p>
					But what if we could?
				</p>

				<p>
					 
				</p>

				<p>
					Some planetary scientists have started warming to the idea that SpaceX's new Starship rocket, with its unprecedented lift capabilities and potentially paradigm-shattering low costs, could open up the Solar System to a new era of exploration. Imagine sending a lander to Europa, which harbors a vast, warm, subsurface ocean. During recent NASA planning meetings, scientists contemplated sending a complex spacecraft, costing billions of dollars, to conduct science on Europa. At best, they were hoping to land a payload of science instruments about the size and mass of a mini-refrigerator there.
				</p>

				<p>
					 
				</p>

				<p>
					With Starship, by contrast, NASA might land a cache of scientific payloads the size of a single-story unfurnished house.
				</p>

				<p>
					 
				</p>

				<p>
					"You can really take advantage of the Starship architecture and get to the outer Solar System in ways we haven't thought about before," Heldmann said. "It could provide a revolutionary new way of exploring these worlds."
				</p>

				<h2>
					Starship’s origins
				</h2>

				<p>
					Engineers at SpaceX have been working seriously on the development of Starship for about five years, and over the last dozen months or so, they have completed several early test flights. Much technical work remains, but the company appears to be well on its way to delivering a superheavy-lift rocket that is fully reusable, low-cost, and potentially capable of delivering as much as 100 tons to the surface of most bodies in the Solar System.
				</p>

				<p>
					 
				</p>

				<p>
					SpaceX and its founder, Elon Musk, view Starship as the key rocket to take humans to Mars and eventually build a self-sustaining settlement there. But such a vehicle would have myriad other uses for science, exploration, and defense purposes.
				</p>

				<p>
					 
				</p>

				<p>
					A highly reliable version of Starship likely remains several years away, but the vehicle could begin a series of orbital test flights in early 2022. NASA's human exploration program now has so much confidence in Starship that the space agency selected the vehicle to serve as the landing system of its Artemis Moon Program. Now, if Starship fails, NASA isn't going back to the Moon.
				</p>

				<p>
					 
				</p>

				<p>
					"Starship can bring unprecedented amounts of payload to Mars and elsewhere," Heldmann said. "Planetary scientists need to be thinking about how we can take advantage of this capability because it’s extraordinary. And if we want to take advantage of these opportunities, to have payloads on the uncrewed test flights, we need to get going."
				</p>

				<p>
					 
				</p>

				<p>
					SpaceX first <a href="https://arstechnica.com/science/2018/08/spacex-organizes-inaugural-conference-to-plan-landings-on-mars/" rel="external nofollow">approached the planetary science community</a> in 2018 with a series of "Mars workshops" that addressed basic questions such as potential landing sites on the planet and gaps in knowledge that need to be filled before people can safely live and work on the surface.
				</p>

				<p>
					 
				</p>

				<p>
					<img alt="51371398490_01e950d359_k-980x1470.jpg" class="ipsImage" data-ratio="75.10" height="540" width="360" src="https://cdn.arstechnica.net/wp-content/uploads/2021/11/51371398490_01e950d359_k-980x1470.jpg">
				</p>

				<figure>
					<figcaption>
						<div>
							Starship is stacked on top of a Super Heavy booster for the first time in August 2021.
						</div>

						<div>
							SpaceX
						</div>
					</figcaption>
				</figure>

				<p>
					The company invited prominent names from the Mars research community, and several dozen participated. Some had already bought into SpaceX's vision, but others were skeptical. Over time, as SpaceX built and tested prototypes, even some of the skeptics began to buy in, believing that Starship was really going to happen.
				</p>

				<p>
					 
				</p>

				<p>
					"As Starship has begun to seem more real, it has changed people's minds," said Tanya Harrison, a planetary scientist and Mars expert who participated in the meetings. "Starship being selected for the lunar missions was a huge credibility boost."
				</p>
			</div>
		</section>
	</div>
</div>

<div data-page="2">
	<div>
		<section>
			<div itemprop="articleBody">
				<h2>
					New white paper
				</h2>

				<p>
					Earlier this year, many of the workshop participants began to recognize the urgency of getting NASA on board with using Starship for science missions. So they wrote a white paper (<a href="https://surveygizmoresponseuploads.s3.amazonaws.com/fileuploads/623127/5489366/111-381503be1c5764e533d2e1e923e21477_HeldmannJenniferL.pdf" rel="external nofollow">see PDF</a>), with Heldmann as the lead author, titled "Accelerating Martian and Lunar Science through SpaceX Starship Missions."
				</p>

				<p>
					 
				</p>

				<p>
					Two dozen other Mars researchers from academia, industry, and SpaceX—Harrison included—signed on to the paper. It issued a clarion call to NASA's leadership to begin providing funding for scientific payloads that could fly on Starship.
				</p>

				<p>
					 
				</p>

				<p>
					"NASA must develop a funded program aligned with the development approach for Starship, including a rapid development schedule, relatively high risk tolerance compared to traditional planetary science missions, and ultimately a high ratio of potential science value for the dollars spent if successful," the scientists and engineers wrote.
				</p>

				<p>
					 
				</p>

				<p>
					Starship's key differentiator is mass. Today, when a scientist plans a mission to explore another world, there are two big constraints: cost and mass. Starship may have some effect on cost by offering more rocket for less money. But the biggest change is that scientists will no longer need to be hyperfocused on mass. They can carry more instruments, more shielding, more whatever. "It completely changes the game," Harrison said.
				</p>

				<p>
					 
				</p>
				For years, NASA's highest planetary exploration priority has been the return of sample rocks from Mars to study in high-tech laboratories on Earth. Finally, the agency has come up with a baseline plan, worked a partnership with the European Space Agency, and started to secure some funding for the <a href="https://www.jpl.nasa.gov/missions/mars-sample-return-msr" rel="external nofollow">Mars Sample Return</a> mission. If all goes well, NASA hopes to bring a few kilograms of rocks back from Mars by 2031.

				<p>
					 
				</p>

				<p>
					Because Starship can take off from other worlds in addition to landing on them, it could completely transform a Mars sample return mission. Instead of being able to handle 2 kilograms of rocks, Starship might be able to return 2 metric tons.
				</p>

				<p>
					 
				</p>

				<p>
					This kind of potential really excites planetary scientists, and not just the younger generation. Brown University's James Head helped NASA select Apollo landing sites in the 1960s and trained the astronauts who landed there. He has since gone on to a distinguished planetary science career.
				</p>

				<p>
					 
				</p>

				<p>
					Head enthusiastically signed the white paper and said he appreciates that SpaceX has a compelling vision and is diligently working toward that goal. At SpaceX's headquarters in Hawthorne, California, Head said he saw the kind of youth, energy, and determination that propelled the Apollo program.
				</p>

				<p>
					 
				</p>

				<p>
					"Being on the floor of the SpaceX factory is the closest I’ve felt to having been in the Apollo program," Head said.
				</p>

				<h2>
					Would NASA?
				</h2>

				<p>
					Creating a program to specifically fund NASA science payloads on Starship seems like a stretch at this time. NASA generally prefers to competitively award programs to multiple bidders, not create a specific program for a specific vehicle.
				</p>

				<p>
					 
				</p>

				<p>
					And even if NASA's leadership decided it wanted to create a Starship-specific program for science payloads, it's doubtful that Congress (or perhaps even the White House) would go along. Members of Congress like jobs in their districts and states, and NASA's traditional contractors provide this. SpaceX, by contrast, focuses heavily on cutting costs and efficiency. It works in comparatively few states and employs fewer subcontractors.
				</p>

				<p>
					 
				</p>

				<p>
					When NASA held a competition for the Human Landing System and ultimately selected SpaceX's Starship as the sole option, Congress protested hotly. But that reaction probably would be tame compared to Congressional fury at selecting a SpaceX-only science payload program to the Moon, Mars, and beyond.
				</p>

				<p>
					 
				</p>

				<p>
					Consider the Mars Sample Return mission. NASA plans to partner with an important ally in space, the European Space Agency, to launch a sample retrieval rover (developed in Europe) and an ascent vehicle, built for NASA by Northrop Grumman. This mission, launching no earlier than 2026, could perhaps fly on United Launch Alliance's Vulcan rocket. Then, a European-built return orbiter would launch on an European Ariane 6 rocket to bring the small cache of samples back to Earth.
				</p>

				<p>
					 
				</p>

				<p>
					Such a mission would likely have a broad array of political support because it would fund multiple US contractors and bolster ties with Europe. By contrast, a SpaceX-only mission on Starship would upset NASA's other contractors, the European Space Agency, and the politicians who back their interests.
				</p>

				<p>
					 
				</p>

				<p>
					Still, the white paper authors felt it was important to underscore the potential value of Starship, despite the political headwinds.
				</p>

				<p>
					 
				</p>

				<p>
					"That is the political reality, you're right," Head said. "On the other hand, if we don't point this out, it will never happen." The development of Starship is a golden opportunity for NASA to rethink how it has done exploration for more than a half- century, he said. Missing that would be a shame.
				</p>

				<p>
					 
				</p>

				<p>
					There are other options available. Several people interviewed for this article suggested that NASA create a "Commercial Mars Payload Services" program, whereby it awards contracts for the development and delivery of science payloads to Mars.
				</p>

				<h2>
					Borrowing from CLPS
				</h2>

				<p>
					This project would be modeled on the agency's Commercial Lunar Payload Services, or CLPS, program, which awards money to private companies to build spacecraft that can carry NASA payloads to the surface of the Moon. NASA has awarded a half-dozen contracts so far to a diverse array of bidders and has a total budget of $2.6 billion through 2028.
				</p>

				<p>
					 
				</p>

				<p>
					Such an idea has already been proposed by scientists in the influential Mars Exploration Program Analysis Group, <a href="https://mepag.jpl.nasa.gov/meeting/2020-06/MASWG-preliminary-results-MEPAG-26June2020.pdf" rel="external nofollow">which suggested that</a> "a Mars-focused CLPS-like program could allow technology development for future exploration as well as delivery of science payloads."
				</p>

				<p>
					 
				</p>

				<p>
					With a commercial Mars program, NASA might offer money to its field centers and the academic community for payload development and then put the responsibility on the scientists to buy transportation to Mars. This might ease some of the political strain on NASA.
				</p>

				<p>
					 
				</p>

				<p>
					NASA's overall leader for science missions, Thomas Zurbuchen, has also championed the CLPS program and its willingness to accept some risk of failure. He said the agency should consider all large rockets coming online in the next few years and take advantage of their capabilities.
				</p>

				<p>
					 
				</p>

				<p>
					"On a 10-year timescale, the availability of heavy launch, whether it is Starship, the Space Launch System, or other large rockets, is a really important ingredient that needs to be considered," Zurbuchen said in an interview.
				</p>

				<p>
					 
				</p>

				<p>
					Another senior official at NASA spoke to Ars and was granted anonymity in order to speak freely.
				</p>

				<p>
					 
				</p>

				<p>
					"I do think the planetary science community is paying attention," the official said. "They’re watching. And I think there are big changes coming. At some point, the risk will be low enough that people will start proposing a Discovery-class mission as a rideshare on a Starship. We just launched Lucy, and Psyche is in development. Both missions were selected at the same time, and both are going to asteroids. Maybe those two could have gone together on a Starship."
				</p>
			</div>
		</section>
	</div>
</div>

<div data-page="3">
	<div>
		<section>
			<div itemprop="articleBody">
				<h2>
					All the things we could do
				</h2>

				<p>
					As scientists start to think less about mass as a constraint, they will run into other barriers to building more planetary spacecraft. Only a relatively small number of people in the world know how to build such vehicles, and training more will take time. There are also a limited number of ground-based facilities where the spacecraft can be subject to vacuum and vibration testing. Then there's cost—the most expensive part of a launch with a scientific probe is not the rocket but the spacecraft.
				</p>

				<p>
					 
				</p>

				<p>
					"Just because Starship is flying, I don’t expect that all of a sudden the Science Mission Directorate’s budget is going to double," the NASA official said.
				</p>

				<p>
					 
				</p>

				<p>
					However, Starship might eventually be able to pare back those costs, especially with the capability to launch frequently.
				</p>

				<p>
					 
				</p>

				<p>
					Consider that SpaceX might provide a regular rideshare flight to Jupiter every two years. Several large and small probes might be carried by a single Starship, using its power and propulsion to reach the Jupiter system. Once there, each spacecraft could fly into their orbits or destinations and rely on Starship for a communications relay back to Earth. This would provide a huge mass and propellant savings on each spacecraft.
				</p>

				<p>
					 
				</p>

				<p>
					SpaceX could fly its first Starship to Mars in 2024; it will probably be little more than a test flight to prove that the massive vehicle can execute a trans-Mars injection and then go into orbit around the red planet. The schedule is tight for NASA to squeeze any science probes onto this first flight, but the next Mars window opens at the end of 2026. That seems like a more reasonable target for both SpaceX and NASA.
				</p>

				<p>
					 
				</p>

				<p>
					There are an impressive range of possibilities for NASA if it wanted to load up Starships headed to Mars in that time frame. NASA's Jet Propulsion Laboratory could build a duplicate of the Perseverance rover with a wholly different set of science instruments. The space agency might fly a pair of Mars Reconnaissance Observer clones to replace its aging communications infrastructure on Mars. Engineers could scale up the Mars Oxygen In-Situ Resource Utilization Experiment, or <a href="https://mars.nasa.gov/mars2020/spacecraft/instruments/moxie/" rel="external nofollow">MOXIE</a>, to produce oxygen in much larger quantities from the Martian atmosphere. NASA could also send a bigger drill to dig deep into the subsurface to see if the interior really is warmer and wetter.
				</p>

				<p>
					 
				</p>

				<p>
					<img alt="1154_Cropped_closeup-980x551.jpeg" class="ipsImage" data-ratio="75.10" height="404" width="720" src="https://cdn.arstechnica.net/wp-content/uploads/2021/11/1154_Cropped_closeup-980x551.jpeg">
				</p>

				<figure>
					<figcaption>
						<div>
							NASA's Perseverance rover takes a selfie on Mars.
						</div>

						<div>
							NASA
						</div>
					</figcaption>
				</figure>

				<p>
					"We'd also be happy to fill up a Starship with Ingenuities," the NASA source said, referring to the <a href="https://arstechnica.com/science/2021/11/nasas-stalwart-mars-helicopter-is-back-and-better-than-ever/" rel="external nofollow">wildly successful helicopter</a> still flying on Mars after landing early this year.
				</p>

				<p>
					 
				</p>

				<p>
					Musk himself recognizes the importance of engaging with the science community and promoting the viability of Starship. One night last month, <a href="https://www.youtube.com/watch?v=da3iF2Np51A" rel="external nofollow">Musk spoke to scientists at the prestigious National Academies</a> for more than an hour, taking question after question from the scientists about Starship, planetary science, and other, more esoteric topics.
				</p>

				<p>
					 
				</p>

				<p>
					"Starship is designed to be a generalized transport mechanism for the greater Solar System," Musk told the scientists. "You could get a 100-ton object to the surface of Europa. It's a lot more than you could do with a smaller rocket. So I think it's very exciting. Obviously, we still have a lot to prove. But architecturally, it is capable of transporting almost any arbitrary mass to any solid surface in the Solar System."
				</p>

				<p>
					 
				</p>

				<p>
					It was somewhat odd—and somewhat endearing—to behold. Here was Elon Musk, the richest person in the world, so contentious on Twitter, so controversial in today's political discourse, seeming to win over some of the smartest people in the country. The scientists were appreciative of his time and eager to learn more about how Starship might help their research.
				</p>

				<p>
					 
				</p>

				<p>
					There may be ice all over the Solar System, but that night, Musk succeeded in melting some of it back here on Earth.
				</p>
			</div>
		</section>
	</div>
</div>

<p>
	 
</p>

<p>
	 
</p>

<p>
	<a href="https://arstechnica.com/science/2021/12/planetary-scientists-are-starting-to-get-stirred-up-by-starships-potential/" rel="external nofollow">Planetary scientists are starting to get stirred up by Starship’s potential</a>
</p>
]]></description><guid isPermaLink="false">3534</guid><pubDate>Wed, 01 Dec 2021 22:25:22 +0000</pubDate></item><item><title>Asteroid-sample return shows water on its rocks&#x2019; surface</title><link>https://nsaneforums.com/news/general-news/asteroid-sample-return-shows-water-on-its-rocks%E2%80%99-surface-r3525/</link><description><![CDATA[<header>
	<h2 itemprop="description">
		A cubic meter of asteroid dust may have as much as 20 liters of water.
	</h2>

	<p>
		<img alt="itokawa07_hayabusa_big.gif" class="ipsImage" data-ratio="53.58" height="382" width="713" src="https://cdn.arstechnica.net/wp-content/uploads/2021/11/itokawa07_hayabusa_big.gif">
	</p>
</header>

<section>
	<div itemprop="articleBody">
		<figure>
			<figcaption>
				<div>
					Itokawa, the original source of the dust grains examined in a new study.
				</div>

				<div>
					<a href="https://apod.nasa.gov/apod/ap070422.html" rel="external nofollow">ISAS, JAXA</a>
				</div>
			</figcaption>
		</figure>

		<p>
			About a decade ago, we were surprised to discover that there's <a href="https://arstechnica.com/science/2010/10/nasa-moon-impact-blasted-into-material-thats-5-water/" rel="external nofollow">a fair amount of water</a> on the <a href="https://arstechnica.com/science/2009/09/three-probes-send-back-unambiguous-evidence-of-lunar-water/" rel="external nofollow">surface of the Moon</a>. Given that the Moon has no atmosphere and receives enough solar radiation to boil any water off, how that water got there wasn't clear. One of the explanations offered at the time was that solar wind sends a steady stream of protons out in the Solar System, and these protons could interact with lunar material to produce water.
		</p>

		<p>
			 
		</p>

		<p>
			Fast-forward a decade and we now have asteroid samples brought back to Earth by two different probes. Working with some of the material obtained by Japan's Hayabusa mission, researchers have found a thin, water-rich layer is present there, too, consistent with being put in place by the solar wind. The researchers behind the finding suggest that this means many Solar System bodies are likely to be fairly water-rich—a reservoir that could have made a big contribution to Earth's oceans.
		</p>

		<h2>
			Only skin deep
		</h2>

		<p>
			The asteroid 25143 Itokawa was the target of the first successful sample-return mission to an asteroid. Itokawa is what's called a "rubble pile," as it's made up of small fragments produced by collisions among asteroids and then slowly gathered together by gravity. Asteroids like this may have fragmented and re-formed multiple times over their history, and they could be composed of portions of more than one body.
		</p>

		<p>
			 
		</p>

		<p>
			A large, international research team took some of the fragments returned to Earth and subjected them to a variety of imaging techniques. The researchers determined that the outermost 40 to 180 nanometers of rock were transformed by their time in space due to bombardment by high-energy radiation. This region also had elevated levels of water and hydroxyl ions (OH-). This finding is consistent with the idea that the water was produced by the interaction between protons in the solar wind and silicate-rich materials in the rocks themselves.
		</p>

		<p>
			 
		</p>

		<p>
			Based on the typical depth of the material that was transformed by the solar wind, the researchers could calculate the amount of water in particles of different sizes. And while there's very little here individually, Itokawa has a lot of small, dust-like particles, which have a high surface area relative to their volume. So it all adds up to an estimated 20 liters of water in every cubic meter of the powdery regolith on the asteroid.
		</p>

		<p>
			 
		</p>

		<p>
			This high fraction is possible because all of the dust on Itokawa has circulated into and out of space over the course of the rubble pile's collision-filled past. So even if something is now buried in the interior, it almost certainly was exposed to the solar wind in the past.
		</p>

		<h2>
			Isotope oddity
		</h2>

		<p>
			Total up all the rubble piles wandering the Solar System, as well as the upper surfaces of the airless bodies, and there's a remarkable amount of water held by the ostensibly dry bodies. That's potentially interesting, should humanity ever manage to make its way out of the Solar System for extended exploration.
		</p>

		<p>
			 
		</p>

		<p>
			But the water also has implications for the Earth's present and past. Most of the Earth's water is thought to have arrived after the massive collision that fragmented a proto-Earth and produced the Moon. Over time, small bodies fell to Earth and brought water with them to create our oceans.
		</p>

		<p>
			 
		</p>

		<p>
			But if we go by the elements in our crust, the bodies that arrived on Earth have a different ratio of hydrogen isotopes from the waters in our ocean. Put differently, the oceans have water that (in isotope terms) is somewhat lighter than the water found in the asteroids that have a composition similar to Earth's. The solar wind, in contrast, has hydrogen isotopes that are overall lighter than what we see in our oceans. So the researchers propose that the solar wind has indirectly helped fill our planet's oceans by producing water on dust particles that eventually fell to Earth.
		</p>

		<p>
			 
		</p>

		<p>
			Finally, the researchers note that the process isn't done. At present, an estimated 30,000 tonnes of dust grains fall from space each year. And these tiny particles will have the highest amount of water per mass of anything exposed to the solar wind. That's still not much water in a given year, but it starts to add up over the billions of years Earth has been around.
		</p>

		<p>
			 
		</p>

		<p>
			Nature Astronomy, 2021. DOI: <a href="http://dx.doi.org/10.1038/s41550-021-01487-w" rel="external nofollow">10.1038/s41550-021-01487-w</a>  (<a href="http://arstechnica.com/science/news/2010/03/dois-and-their-discontents-1.ars" rel="external nofollow">About DOIs</a>).
		</p>
	</div>
</section>

<p>
	 
</p>

<p>
	 
</p>

<p>
	<a href="https://arstechnica.com/science/2021/11/solar-wind-may-have-made-water-all-over-the-solar-system/" rel="external nofollow">Asteroid-sample return shows water on its rocks’ surface</a>
</p>
]]></description><guid isPermaLink="false">3525</guid><pubDate>Wed, 01 Dec 2021 06:22:18 +0000</pubDate></item><item><title>6-foot social distancing rule doesn&#x2019;t protect from COVID-19 whether indoors or outdoors</title><link>https://nsaneforums.com/news/general-news/6-foot-social-distancing-rule-doesn%E2%80%99t-protect-from-covid-19-whether-indoors-or-outdoors-r3519/</link><description><![CDATA[<p>
	CAMBRIDGE, United Kingdom — Although the “six-foot rule” has been a staple of coronavirus safety measure since 2020, is it really doing anything to keep people healthy? A new study finds the answer to that appears to be a resounding no. Scientists from the University of Cambridge say the social distancing rule of six feet does not protect against catching COVID-19, even outdoors.
</p>

<p>
	 
</p>

<p>
	The team calls the social distancing rule an “arbitrary measurement” of safety in the absence of masks. It could have been set anywhere between three to 10 feet, depending on the risk tolerance of the local public health authority putting out the mandate.
</p>

<p>
	 
</p>

<p>
	Infected individuals spread the virus through coughing, speaking, and even breathing. People expel larger droplets that eventually settle on surfaces or break into smaller aerosols that may float through the air. The study used computer modelling to quantify how these infectious particles travel. Results show coughs vary widely when it comes to expelling particles.
</p>

<p>
	 
</p>

<p>
	“I remember hearing lots about how COVID-19 was spreading via door handles in early 2020, and I thought to myself if that were the case, then the virus must leave an infected person and land on the surface or disperse in the air through fluid mechanical processes,” says lead author Professor Epaminondas Mastorakos in a university release.
</p>

<p>
	 
</p>

<p>
	<span style="font-size:20px;"><strong>No masks lead to an unknown dynamic when coughing</strong></span>
</p>

<p>
	<br />
	Scientists say the findings in the Physics of Fluids underline the continued importance of vaccination, ventilation, and masks heading into winter.
</p>

<p>
	Early in the pandemic, health experts focused on hand washing and surface cleaning. However, Cambridge engineers note it’s been clear for nearly two years that COVID spreads through airborne transmission. They have developed various programs to investigate how the virus behaves in different environments.
</p>

<p>
	 
</p>

<p>
	“One part of the way that this disease spreads is virology: how much virus you have in your body, how many viral particles you expel when you speak or cough,” adds first author Dr. Shrey Trivedi. “But another part of it is fluid mechanics: what happens to the droplets once they’re expelled, which is where we come in. As fluid mechanics specialists, we’re like the bridge from virology of the emitter to the virology of the receiver and we can help with risk assessment.”
</p>

<p>
	 
</p>

<p>
	Simulations showed how much of the virus would reach another person in the same room from a cough containing 1,000 droplets. The researchers found there isn’t a sharp cut-off once the droplets spread beyond two meters.
</p>

<p>
	 
</p>

<p>
	When a person coughs and isn’t wearing a mask, most of the larger droplets will fall on nearby surfaces, but smaller droplets suspended in the air can quickly and easily spread well beyond the six-foot mark. How far and how quickly these aerosols spread will depend on the quality of ventilation in a room. In addition to the variables surrounding mask-wearing and ventilation, there’s also a high degree of variability.
</p>

<p>
	 
</p>

<p>
	“Each time we cough, we may emit a different amount of liquid, so if a person is infected with COVID-19, they could be emitting lots of virus particles or very few, and because of the turbulence they spread differently for every cough,” Trivedi continues.
</p>

<p>
	 
</p>

<p>
	<span style="font-size:20px;"><strong>The 6-foot rule may only be good for COVID messaging</strong></span>
</p>

<p>
	<br />
	The team’s calculations took into account turbulent flow and detailed descriptions of droplet motion and evaporation.
</p>

<p>
	 
</p>

<p>
	“Even if I expel the same number of droplets every time I cough, because the flow is turbulent, there are fluctuations,” Mastorakos says. “If I’m coughing, fluctuations in velocity, temperature and humidity mean that the amount someone gets at the two-meter mark can be very different each time.”
</p>

<p>
	 
</p>

<p>
	The six-foot rule is an effective and easy-to-remember message for the public. However, the study finds it isn’t a mark of safety given the large number of variables associated with an airborne virus. Vaccination, ventilation, and masks – while not 100 percent effective – are vital for containing the pandemic.
</p>

<p>
	 
</p>

<p>
	“We’re all desperate to see the back of this pandemic, but we strongly recommend that people keep wearing masks in indoor spaces such as offices, classrooms and shops,” Mastorakos concludes. “There’s no good reason to expose yourself to this risk as long as the virus is with us.”
</p>

<p>
	 
</p>

<p>
	The researchers are carrying out similar simulations for spaces such as lecture rooms to assess the risk as people spend more time indoors. The World Health Organization recommends a distance of at least three feet (one meter) from others — even if they don’t appear to be sick. WHO also advises people to avoid crowds and close contact and to wear a properly fitted mask in poorly ventilated rooms.
</p>

<p>
	 
</p>

<div class="ipsEmbeddedVideo">
	<div>
		<iframe allowfullscreen="" frameborder="0" height="113" width="200" data-embed-src="https://www.youtube.com/embed/XFyaT_r_vBE?feature=oembed"></iframe>
	</div>
</div>

<p>
	 
</p>

<p>
	<em>South West News Service writer Mark Waghorn contributed to this report.</em>
</p>

<p>
	 
</p>

<p>
	<strong><a href="https://www.studyfinds.org/6-foot-rule-doesnt-protect-covid/" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3519</guid><pubDate>Tue, 30 Nov 2021 15:27:41 +0000</pubDate></item><item><title>Arctic Ocean started getting warmer decades earlier than we thought - study</title><link>https://nsaneforums.com/news/general-news/arctic-ocean-started-getting-warmer-decades-earlier-than-we-thought-study-r3517/</link><description><![CDATA[<p>
	<span style="color:#16a085;"><span style="font-size:24px;">The Arctic Ocean has been getting warmer since the beginning of the 20th century – decades earlier than records suggest – due to warmer water flowing into the delicate polar ecosystem from the Atlantic Ocean.</span></span>
</p>

<p>
	 
</p>

<p>
	An international group of researchers reconstructed the recent history of ocean warming at the gateway to the Arctic Ocean in a region called the Fram Strait, between Greenland and Svalbard.
</p>

<p>
	 
</p>

<p>
	Using the chemical signatures found in marine microorganisms, the researchers found that the Arctic Ocean began warming rapidly at the beginning of the last century as warmer and saltier waters flowed in from the Atlantic – a phenomenon called Atlantification – and that this change likely preceeded the warming documented by modern instrumental measurements. Since 1900, the ocean temperature has risen by approximately 2 degrees Celsius, while sea ice has retreated and salinity has increased.
</p>

<p>
	 
</p>

<p>
	The <a href="https://www.science.org/doi/10.1126/sciadv.abj2946" rel="external nofollow"><span style="color:#16a085;">results</span></a>, reported in the journal Science Advances, provide the first historical perspective on Atlantification of the Arctic Ocean and reveal a connection with the North Atlantic that is much stronger than previously thought. The connection is capable of shaping Arctic climate variability, which could have important implications for sea-ice retreat and global sea-level rise as the polar ice sheets continue to melt.
</p>

<p>
	 
</p>

<p>
	All of the world’s oceans are warming due to climate change, but the Arctic Ocean, the smallest and shallowest of the world’s oceans, is warming fastest of all.
</p>

<p>
	 
</p>

<p>
	“The rate of warming in the Arctic is more than double the global average, due to feedback mechanisms,” said co-lead author Dr Francesco Muschitiello from Cambridge’s Department of Geography. “Based on satellite measurements, we know that the Arctic Ocean has been steadily warming, in particular over the past 20 years, but we wanted to place the recent warming into a longer context.”
</p>

<p>
	 
</p>

<p>
	Atlantification is one of the causes of warming in the Arctic, however instrumental records capable of monitoring this process, such as satellites, only go back about 40 years.
</p>

<p>
	 
</p>

<p>
	As the Arctic Ocean gets warmer, it causes the ice in the polar region to melt, which in turn affects global sea levels. As the ice melts, it exposes more of the ocean’s surface to the sun, releasing heat and raising air temperatures. As the Arctic continues to warm, it will melt the permafrost, which stores huge amounts of methane, a far more damaging greenhouse gas than carbon dioxide.
</p>

<p>
	 
</p>

<p style="text-align:center;">
	<img alt="fieldwork5-3000x4000.jpeg" class="ipsImage" data-ratio="75.10" height="540" width="405" src="https://www.cam.ac.uk/sites/www.cam.ac.uk/files/shorthand/228321/cErrn4vDEn/assets/ib4QiFnDwF/fieldwork5-3000x4000.jpeg" />
</p>

<p style="text-align:center;">
	 
</p>

<p>
	The researchers used geochemical and ecological data from ocean sediments to reconstruct the change in water column properties over the past 800 years. They precisely dated sediments using a combination of methods and looked for diagnostic signs of Atlantification, like change in temperature and salinity.
</p>

<p>
	 
</p>

<p>
	 “When we looked at the whole 800-year timescale, our temperature and salinity records look pretty constant,” said co-lead author Dr Tesi Tommaso from the Institute of Polar Sciences of the National Research Council in Bologna. “But all of a sudden at the start of the 20th century, you get this marked change in temperature and salinity – it really sticks out.”
</p>

<p>
	 
</p>

<p>
	“The reason for this rapid Atlantification of at the gate of the Arctic Ocean is intriguing,” said Muschitiello. “We compared our results with the ocean circulation at lower latitudes and found there is a strong correlation with the slowdown of dense water formation in the Labrador Sea. In a future warming scenario, the deep circulation in this subpolar region is expected to further decrease because of the thawing of the Greenland ice sheet. Our results imply that we might expect further Arctic Atlantification in the future because of climate change.”
</p>

<p>
	 
</p>

<p style="text-align:center;">
	<img alt="fieldwork4-4000x3000.jpeg" class="ipsImage" data-ratio="75.10" height="540" width="720" src="https://www.cam.ac.uk/sites/www.cam.ac.uk/files/shorthand/228321/cErrn4vDEn/assets/p6AEmcNIC7/fieldwork4-4000x3000.jpeg" />
</p>

<p style="text-align:center;">
	 
</p>

<p>
	The researchers say that their results also expose a possible flaw in climate models, because they do not reproduce this early Atlantification at the beginning of the last century.
</p>

<p>
	 
</p>

<p>
	“Climate simulations generally do not reproduce this kind of warming in the Arctic Ocean, meaning there’s an incomplete understanding of the mechanisms driving Atlantification,” said Tommaso. “We rely on these simulations to project future climate change, but the lack of any signs of an early warming in the Arctic Ocean is a missing piece of the puzzle.” 
</p>

<p>
	 
</p>

<p>
	Francesco Muschitiello is a Fellow of Sidney Sussex College, Cambridge.
</p>

<p>
	 
</p>

<p>
	<strong>Reference:</strong>
</p>

<p>
	<br />
	Tesi Tommaso et al. <em><a href="https://www.science.org/doi/10.1126/sciadv.abj2946" rel="external nofollow">‘<span style="color:#16a085;">Rapid Atlantification along the Fram Strait at the beginning of the 20th century.’</span></a><span style="color:#16a085;"> </span></em>Science Advances (2021). DOI: 10.1126/sciadv.abj2946
</p>

<p>
	 
</p>

<p>
	The text in this work is licensed under a <span style="color:#16a085;"><em>Creative Commons Attribution 4.0 International License</em></span>.
</p>

<p>
	 
</p>

<p>
	<strong><a href="https://www.cam.ac.uk/stories/arcticocean" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3517</guid><pubDate>Thu, 01 Jan 1970 00:00:00 +0000</pubDate></item><item><title>In the wrong hands, vaccination statistics can prove deadly. Simpson's Paradox shows why</title><link>https://nsaneforums.com/news/general-news/in-the-wrong-hands-vaccination-statistics-can-prove-deadly-simpsons-paradox-shows-why-r3516/</link><description><![CDATA[<p>
	There has been much discussion of late about data published on 1 November, 2021, by the Office for National Statistics (ONS). It is titled "Deaths involving COVID-19 by vaccination status, England: deaths occurring between 2 January and 24 September 2021."
</p>

<p>
	 
</p>

<p>
	The raw statistics show death rates in England for people aged 10 to 59, listing vaccination status separately.
</p>

<p>
	 
</p>

<p>
	Counterintuitively, these statistics show that the death rates for the vaccinated in this age grouping were greater than for the unvaccinated. These numbers have since been heavily promoted and highlighted on social media by anti-vaccine advocates, who use them to argue that vaccination increases the risk of death.
</p>

<p>
	 
</p>

<p>
	The claim is strange, though, because we know from efficacy and effectiveness studies that COVID-19 vaccines offer strong protection against severe disease. For example, the efficiency and effectiveness of the Pfizer-BioNTech vaccine has been shown to be well over 90% in this regard in the most recent studies.
</p>

<p>
	 
</p>

<p>
	Vaccine efficacy of 90% means that you have a 90% reduced risk compared to an otherwise similar unvaccinated person, based on controlled randomized trials, while vaccine effectiveness refers to real-world outcomes. On either measure, vaccines work very well indeed. So what's going on here?
</p>

<p>
	 
</p>

<p>
	Well, closer inspection of the ONS report reveals that over the period of the study, from January to September 2021, the age-adjusted risk of death involving COVID-19 was 32 times greater among unvaccinated people compared to fully vaccinated people. But hold on! How can we square this with the data from the table listing death rates of those aged 10 to 59 by vaccination status?
</p>

<p>
	 
</p>

<p>
	For the answer we turn to a classic statistical artifact known as Simpson's Paradox, which seems to pop up and create misleading conclusions all over the place.
</p>

<p>
	 
</p>

<p>
	It is a consequence of the way that data is presented.
</p>

<p>
	 
</p>

<p>
	Essentially, Simpson's Paradox can arise when observing a feature of a broad, widely drawn group, where there is an uneven distribution of the population within this group, for example by age or vaccination status. Ignorance of the implications of Simpson's Paradox can generate misleading conclusions, which can be, and in this case are, very dangerous.
</p>

<p>
	 
</p>

<p>
	The paradox in these particular ONS statistics arises specifically because death rates increase dramatically with age, so that at the very top end of this age band, for example, mortality rates are about 80 times as high as at the very bottom end. A similar pattern is observed between vaccination rates and age. For example, in the 10 to 59 data set more than half of those vaccinated are over the age of 40.
</p>

<p>
	 
</p>

<p>
	Those who are in the upper ranges of the wide 10 to 59 age band are, therefore, both more likely to have been vaccinated and also more likely to die if infected with COVID-19 or for any other reason, and vice versa. Age is acting, in the terminology of statistics, as a confounding variable, being positively related to both vaccination rates and death rates.
</p>

<p>
	 
</p>

<p>
	Put another way, you are more likely to die in a given period if you are older and you are also more likely to be vaccinated if you are older. It is age that is driving up death rates not the vaccinations. Without the vaccinations, deaths would be hugely greater from COVID-19.
</p>

<p>
	 
</p>

<p>
	So what if we divide the 10 to 59 group into smaller age groups? If we break down the band into narrower age ranges, such as 10 to 19, 20 to 29, 30 to 39, 40 to 49, and 50 to 59, we find that the counter-intuitive headline finding immediately disappears. In each age band, the death rates of the vaccinated are vastly lower than those of the unvaccinated. This also applies in the higher age bands—60 to 69, 70 to 79, and 80 plus.
</p>

<p>
	 
</p>

<p>
	Basically, unvaccinated people are much younger on average, and therefore less likely to die.
</p>

<p>
	 
</p>

<p>
	Yet there are those out there who are more than happy to use these statistics to mislead. The consequence is that many who would otherwise choose to be vaccinated might refuse to do so.
</p>

<p>
	 
</p>

<p>
	In truth, the age-adjusted risk of deaths involving coronavirus (COVID-19) over the first nine months of this year was in fact 32 times greater in the unvaccinated than the fully vaccinated.
</p>

<p>
	 
</p>

<p>
	This is a hugely important statistic, and we must not let statistical manipulation be used to obscure this critical information. The lives of countless people really do depend on us exposing this truth.
</p>

<p>
	 
</p>

<p>
	<strong><a href="https://medicalxpress.com/news/2021-11-wrong-vaccination-statistics-deadly-simpson.html" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3516</guid><pubDate>Tue, 30 Nov 2021 14:37:12 +0000</pubDate></item><item><title>James Webb Space Telescope cleared for late December launch</title><link>https://nsaneforums.com/news/general-news/james-webb-space-telescope-cleared-for-late-december-launch-r3510/</link><description><![CDATA[<header>
	<h2 itemprop="description">
		Webb will launch on a European-built Ariane 5 rocket no earlier than Dec. 22.
	</h2>

	<p>
		<img alt="James-Webb-artists-impression-800x800.jp" class="ipsImage" data-ratio="75.10" height="540" width="540" src="https://cdn.arstechnica.net/wp-content/uploads/2016/09/James-Webb-artists-impression-800x800.jpg">
	</p>
</header>

<section>
	<div itemprop="articleBody">
		<figure>
			<figcaption>
				<div>
					Artist's impression of the James Webb Space Telescope in space.
				</div>

				<div>
					<a href="https://www.flickr.com/photos/nasawebbtelescope/sets/72157624413830771" rel="external nofollow">NASA</a>
				</div>
			</figcaption>
		</figure>

		<p>
			Following a scare last week, NASA and European Space Agency officials have said they will continue launch preparations for the James Webb Space Telescope. The $10 billion instrument is slated to launch on a European-built Ariane 5 rocket no earlier than December 22.
		</p>

		<p>
			 
		</p>

		<p>
			NASA said that engineers have completed additional testing to ensure the telescope's readiness for flight, and fueling operations began on November 25. The telescope has 20 small thrusters for maneuvering and will be filled with about 240 liters of hydrazine fuel and dinitrogen tetroxide oxidizer. The fueling process will take about 10 days.
		</p>

		<p>
			 
		</p>

		<p>
			The decision to press ahead with the Webb telescope's launch countdown counts as good news after a slightly worrisome announcement one week ago. On November 22, <a href="https://arstechnica.com/science/2021/11/an-incident-with-the-james-webb-space-telescope-has-occurred/" rel="external nofollow">NASA said</a> it would delay the space telescope's planned launch by a few days to investigate an "anomaly" during processing operations at the launch site in Kourou, French Guiana.
		</p>

		<p>
			 
		</p>

		<p>
			"Technicians were preparing to attach Webb to the launch vehicle adapter, which is used to integrate the observatory with the upper stage of the Ariane 5 rocket," NASA said in a blog post. "A sudden, unplanned release of a clamp band—which secures Webb to the launch vehicle adapter—caused a vibration throughout the observatory."
		</p>

		<p>
			 
		</p>

		<p>
			The problem occurred earlier in the month, and NASA convened an anomaly review board to investigate and conduct additional testing. Following those tests, engineers concluded that the observatory had not been damaged by the vibrations from the clamp band's release.
		</p>

		<p>
			 
		</p>

		<p>
			The much-anticipated launch of the space telescope is only the beginning of the road for Webb to begin science operations, however. Its launch late this year will set up a nerve-wracking holiday season for NASA managers and the scientists who hope to use the powerful telescope to look back and see some of the earliest galaxies to form in the universe.
		</p>

		<p>
			 
		</p>

		<p>
			After its launch, Webb will need to travel about 1.5 million km from Earth to the L2 Lagrange Point beyond the Moon. There, it will be able to maintain a stable position without using much on-board propulsion. Along the way, and once there, some 50 deployments of the large, folded-up telescope will be necessary to prepare for scientific observations.
		</p>

		<p>
			 
		</p>

		<p>
			This process will involve nearly 350 single-point failures, and if something goes wrong, it would scuttle the deployment without hope of repair.
		</p>
	</div>
</section>

<p>
	 
</p>

<p>
	 
</p>

<p>
	<a href="https://arstechnica.com/science/2021/11/james-webb-space-telescope-cleared-for-late-december-launch/" rel="external nofollow">James Webb Space Telescope cleared for late December launch</a>
</p>
]]></description><guid isPermaLink="false">3510</guid><pubDate>Mon, 29 Nov 2021 22:22:29 +0000</pubDate></item><item><title>'Gangotri wave' connecting two of Milky Way's spiral arms discovered</title><link>https://nsaneforums.com/news/general-news/gangotri-wave-connecting-two-of-milky-ways-spiral-arms-discovered-r3503/</link><description><![CDATA[<p>
	A team of researchers from Germany, France and the U.K. has discovered a long thin filament of dense gas connecting two of the Milky Way galaxy's spiral arms. In their paper published in <em>The Astrophysical Journal Letters</em>, the group describes their work studying carbon monoxide gas in the galaxy.
</p>

<p>
	 
</p>

<p>
	Prior research has shown that other galaxies have features called feathers—long gas filaments with barbs that look from Earth like feathers. But because it is very difficult to study the Milky Way galaxy from an Earth perspective, no such features have been seen, until now.
</p>

<p>
	 
</p>

<p>
	In their work, the researchers were studying concentrations of carbon monoxide gas in data from the APEX telescope in San Pedro de Atacama, Chile. They noticed concentrations that had not been seen before, and after taking a closer look, discovered that it was part of a large gas formation that extended from near the center of the galaxy outward, connecting two of the arms that give the galaxy its distinctive look.
</p>

<p>
	 
</p>

<p>
	The researchers named the formation the<span style="color:#c0392b;"> <strong>Gangotri wave</strong></span>—<span style="color:#c0392b;"><strong>an homage to the massive glacier whose melting gives rise to the Ganges River</strong></span>. <span style="color:#c0392b;"><strong>In India, the Milky Way galaxy is known as Akasha Ganga.</strong></span> The newly discovered feather spans approximately 5.6764e+16 to 1.22989e+17 kilometers in reaching between the two arms and is approximately 1.6083242e+17 kilometers from the rotational center of the galaxy. They have also estimated its mass to be approximately equal to nine million suns. Prior to the new discovery, all of the gas tendrils found in the Milky Way have aligned with the spiral arms.
</p>

<p>
	 
</p>

<p>
	The researchers found that the Gangotri wave has another unique and interesting feature in that it is not as straight as expected. Instead, it zig-zags back and forth along its length in a pattern similar to a sine wave. The researchers were not able to explain the strange phenomenon but note that some force must be at play—a force that is likely to be the focus of many upcoming research efforts. The team plans to continue their study of gases in the Milky Way, this time actively looking for new feathers.
</p>

<p>
	 
</p>

<p>
	<strong><a href="https://phys.org/news/2021-11-gangotri-milky-spiral-arms.html" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3503</guid><pubDate>Sun, 28 Nov 2021 14:42:09 +0000</pubDate></item><item><title>Rare hunting scene raises questions over polar bear diet</title><link>https://nsaneforums.com/news/general-news/rare-hunting-scene-raises-questions-over-polar-bear-diet-r3502/</link><description><![CDATA[<p>
	A polar bear chases a reindeer into the water, drags it ashore and devours it, in a striking scene caught on film for the first time.
</p>

<p>
	 
</p>

<p>
	With sea ice melting, the king of the Arctic may be changing its diet.
</p>

<p>
	 
</p>

<p>
	The dramatic spectacle played out in Norway's Svalbard archipelago on August 21, 2020—in summer, the sea ice retreats and takes with it the seals that make up the polar bear's main source of food.
</p>

<p>
	 
</p>

<p>
	A research team from a nearby Polish scientific station watched it happen and caught for the first time on camera a polar bear hunting a reindeer.
</p>

<p>
	The video shows a young female chasing a male reindeer into the icy waters, catching and drowning it, then pulling it on shore and making a meal of it.
</p>

<p>
	 
</p>

<p>
	"The whole situation was so amazing that it was like watching a documentary," said Izabela Kulaszewicz, a biologist at the University of Gdansk.
</p>

<p>
	 
</p>

<p>
	"You could almost hear the voice of a narrator in the background saying that you absolutely have to watch this event because we will most likely never see anything like it again," she told AFP.
</p>

<p>
	 
</p>

<p>
	<strong>Down to 'modern media' ?</strong>
</p>

<p>
	 
</p>

<p>
	The scene was so unusual that she co-wrote Polar Biology with two other researchers.
</p>

<p>
	 
</p>

<p>
	In it, they argued that the incident was one of a series of observations that suggest polar bears are increasingly preying on terrestrial animals to make up for their limited access to seals.
</p>

<p>
	 
</p>

<p style="text-align:center;">
	<img alt="in-svalbard-just-over.jpg" class="ipsImage" data-ratio="73.89" height="478" width="720" src="https://scx1.b-cdn.net/csz/news/800a/2021/in-svalbard-just-over.jpg" />
</p>

<p style="text-align:center;">
	<span style="font-size:12px;"><em>In Svalbard, just over 1,000 kilometres (620 miles) from the North Pole, some 300 sedentary polar bears live alongside around 20,000 reindeer.</em></span>
</p>

<p style="text-align:center;">
	 
</p>

<p>
	In Svalbard, just over 1,000 kilometres (620 miles) from the North Pole and where signposts warn of the danger of polar bears, some 300 sedentary bears live alongside around 20,000 reindeer.
</p>

<p>
	 
</p>

<p>
	According to the article's authors, there are indications that polar bears have been hunting reindeer more frequently in recent decades.
</p>

<p>
	 
</p>

<p>
	They say that two factors are at play: the retreating sea ice is stranding the bears on land for longer periods, and the number of reindeer has been steadily rising on Svalbard since a 1925 hunting ban.
</p>

<p>
	 
</p>

<p>
	Eating reindeer is therefore a matter of both necessity and opportunity for the furry white beast, they suggest.
</p>

<p>
	 
</p>

<p>
	However, other experts caution against reading too much into the incident.
</p>

<p>
	 
</p>

<p>
	"If polar bears were killing reindeer back in the 1950s and 60s, it would have been very rare to have been seen, as there were few people, few bears, and few reindeer" in Svalbard at the time, said Andrew Derocher, a professor at the University of Alberta.
</p>

<p>
	 
</p>

<p>
	"Now, with modern media, everyone has a camera, social media and the 'news' spreads fast," he added.
</p>

<p>
	 
</p>

<p>
	<strong>Opportunistic hunters</strong>
</p>

<p>
	 
</p>

<p>
	While high-fat, high-calorie ringed and bearded seals make up their main diet, polar bears are also known to feed on eggs, birds, rodents and even dolphins.
</p>

<p>
	 
</p>

<p>
	Weighing between 70 and 90 kilos (155 and 200 pounds) as adults, reindeer would be a good complement for the bears during the lean summer period, which has grown longer due to global warming.
</p>

<p>
	 
</p>

<p style="text-align:center;">
	<img alt="key-facts-about-the-po.jpg" class="ipsImage" data-ratio="68.19" height="442" width="720" src="https://scx1.b-cdn.net/csz/news/800a/2021/key-facts-about-the-po.jpg" />
</p>

<p style="text-align:center;">
	<span style="font-size:12px;"><em>Key facts about the polar bear, apex predator of the Arctic.</em></span>
</p>

<p style="text-align:center;">
	 
</p>

<p>
	Two days after the Polish researchers filmed their video, the same polar bear was observed devouring another reindeer carcass.
</p>

<p>
	 
</p>

<p>
	"Reindeer can be important, at least for some polar bears when they have to stay on land for extended periods," said Norwegian expert Jon Aars, co-author of the article.
</p>

<p>
	 
</p>

<p>
	Experts note, however, that the new diet would not make a difference in bolstering the animal's population size.
</p>

<p>
	 
</p>

<p>
	"While an occasional successful predation attempt on reindeer may be good in the short-term for an individual bear or two (and the media), I think there is little significance at the population level for either polar bears or reindeer," said professor Ian Stirling, of the Canadian Wildlife Service.
</p>

<p>
	Polar bears are strong swimmers—their Latin name is Ursus maritimus—but they can't keep up with reindeer on long distances on land.
</p>

<p>
	 
</p>

<p>
	Elsewhere in the Arctic, caribou—as North American reindeer are known—are not as vulnerable as their Svalbard cousins, whose wariness seems to have dissipated since the hunting ban.
</p>

<p>
	 
</p>

<p>
	Caribou "are also larger animals and have co-evolved with land predators, namely wolves, wolverines, and barren ground grizzlies, making them more challenging prey," said Geoff York, of conservation organisation Polar Bears International.
</p>

<p>
	 
</p>

<p>
	The future looks especially ominous for Svalbard's polar bears.
</p>

<p>
	 
</p>

<p>
	"There's not enough ice to sustain a polar bear population," Derocher said.
</p>

<p>
	 
</p>

<p>
	"I suspect that given the trend, the Barents Sea polar bear population—which includes Svalbard—is one that will disappear this century."
</p>

<p>
	 
</p>

<p>
	<strong><a href="https://phys.org/news/2021-11-rare-scene-polar-diet.html" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3502</guid><pubDate>Sun, 28 Nov 2021 14:37:56 +0000</pubDate></item><item><title>Aspirin increases the risk of heart failure by over 25%</title><link>https://nsaneforums.com/news/general-news/aspirin-increases-the-risk-of-heart-failure-by-over-25-r3498/</link><description><![CDATA[<p>
	SOPHIA ANTIPOLIS, France — Aspirin is one of the most common pain relievers in the world, but a new study finds it may be contributing to heart failure. Researchers with the European Society of Cardiology find taking aspirin raises the risk of heart failure among people with at least one pre-existing health risk. These include smoking, being obese, having high blood pressure, high cholesterol, diabetes, or cardiovascular disease.
</p>

<p>
	 
</p>

<p>
	Aspirin has a complicated medical history. While some studies find regularly taking aspirin can help protect against illnesses like COVID-19 and cancer, others show it actually does more harm than good.
</p>

<p>
	 
</p>

<p>
	“This is the first study to report that among individuals with a least one risk factor for heart failure, those taking aspirin were more likely to subsequently develop the condition than those not using the medication,” says study author Dr. Blerim Mujaj of the University of Freiburg in a media release. “While the findings require confirmation, they do indicate that the potential link between aspirin and heart failure needs to be clarified.”
</p>

<p>
	 
</p>

<p>
	<span style="font-size:20px;"><strong>Older adults at high risk from aspirin use</strong></span>
</p>

<p>
	 
</p>

<p>
	In a study of nearly 31,000 people at risk of developing heart failure, the team found that aspirin users saw their chances of a heart failure diagnosis go up by 26 percent. Researchers defined “at risk” as anyone with a pre-existing health condition.
</p>

<p>
	 
</p>

<p>
	All of the participants were over the age of 40 and free of heart failure at the start of the experiment. The team recorded each person’s use of aspirin, separating them into two groups — users and non-users. Researchers followed up with the participants (who had an average age of 67) over a five-year period and after a person’s first fatal or non-fatal heart failure incident requiring hospitalization.
</p>

<p>
	 
</p>

<p>
	After accounting for influential factors like gender, weight, age, alcohol use, the use of medications, and various measures of health, the team concluded that aspirin independently contributes to increasing heart failure risk by more than a quarter among people with pre-existing health issues. Overall, 7,698 participants were taking aspirin and 1,330 developed heart failure over the next 5.3 years.
</p>

<p>
	 
</p>

<p>
	<span style="font-size:20px;"><strong>Even healthy people face dangers</strong></span>
</p>

<p>
	 
</p>

<p>
	To confirm their results, study authors compared the readings among aspirin users and non-users. They also examined the 74 percent of the study group that was free of cardiovascular disease (22,690 people) and found that using aspirin increased their risk of heart failure by 27 percent as well.
</p>

<p>
	 
</p>

<p>
	“This was the first large study to investigate the relationship between aspirin use and incident heart failure in individuals with and without heart disease and at least one risk factor. Aspirin is commonly used – in our study one in four participants were taking the medication. In this population, aspirin use was associated with incident heart failure, independent of other risk factors,” Dr. Mujaj concludes.
</p>

<p>
	 
</p>

<p>
	“Large multinational randomized trials in adults at risk for heart failure are needed to verify these results. Until then, our observations suggest that aspirin should be prescribed with caution in those with heart failure or with risk factors for the condition.”
</p>

<p>
	 
</p>

<p>
	The findings appear in the journal <span style="color:#c0392b;"><a href="https://onlinelibrary.wiley.com/doi/10.1002/ehf2.13688" rel="external nofollow">ESC Heart Failure</a></span>.
</p>

<p>
	 
</p>

<p>
	<strong><a href="https://www.studyfinds.org/aspirin-heart-failure-risk/" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3498</guid><pubDate>Sat, 27 Nov 2021 14:49:43 +0000</pubDate></item><item><title>Moderna says it will develop booster shot for new COVID variant</title><link>https://nsaneforums.com/news/general-news/moderna-says-it-will-develop-booster-shot-for-new-covid-variant-r3495/</link><description><![CDATA[<p>
	The US pharmaceutical company Moderna said Friday it will develop a booster shot against the new Omicron variant of the coronavirus.
</p>

<p>
	 
</p>

<p>
	It is one of three strategies the company is working to address the new threat, including a higher dose of its existing vaccine, Moderna said.
</p>

<p>
	 
</p>

<p>
	"The mutations in the Omicron variant are concerning and for several days, we have been moving as fast as possible to execute our strategy to address this variant," said Moderna CEO Stephane Bancel.
</p>

<p>
	 
</p>

<p>
	<strong><a href="https://medicalxpress.com/news/2021-11-moderna-booster-shot-covid-variant.html" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3495</guid><pubDate>Sat, 27 Nov 2021 14:15:29 +0000</pubDate></item><item><title>The melancholy decline of the semicolon</title><link>https://nsaneforums.com/news/general-news/the-melancholy-decline-of-the-semicolon-r3494/</link><description><![CDATA[<p>
	<span style="font-size:20px;">Researchers found that it is becoming rarer in British fiction</span>
</p>

<p>
	 
</p>

<p>
	The semicolon is a profound public mystery; the only punctuation mark that regularly unites readers and writers in deep-seated repugnance. Time to celebrate then — this week researchers at Lancaster University announced that semicolon use is becoming rarer in British fiction, falling in use by 25% over the last 30 years.
</p>

<p>
	 
</p>

<p>
	In 2017, author Ben Blatt discovered that semicolon use dropped by about 70% from 1800 to 2000. The ghosts of several authors are now rejoicing.
</p>

<p>
	 
</p>

<p>
	Writers like George Orwell, who called semicolons “an unnecessary stop”. Or Edgar Allan Poe, who preferred the dash. Or Kurt Vonnegut, who famously advised against their use, saying “All they do is show you’ve been to college.” The symbol is facing the same melancholy fate as the dodo, the dinosaur, and the Soviet Union. Extinction.
</p>

<p>
	 
</p>

<p>
	When the semicolon first appeared in the work of the Renaissance scholar and printer Aldus Pius Manutius, in a book describing a climb to the summit of Mount Etna, it was a hybrid between a comma and a colon. Its function was to prolong a pause, or to create a more unmistakable separation between clauses in a sentence.
</p>

<p>
	 
</p>

<p>
	Nothing has changed; semicolons are exactly what Manutius invented them to be in 1494. Their decline in fiction, and the suspicion that surrounds their use in everyday communication, tells us a story about the times we live in.
</p>

<p>
	 
</p>

<p>
	Lancaster’s linguists believe that the end of the semicolon, along with shrinking sentence lengths in novels, is a reflection of a society addicted to social media. The shift, commented Justin Tora of the University of Galway, is part of a “more realistic way” of writing for the modern age.
</p>

<p>
	 
</p>

<p>
	They may be right. The semicolon is an element of language that communicates stops, pauses, reflections, and cigarette breaks within a sentence. It connects loose ends with disparate ideas; the semicolon lets you have it both ways. Today having it both ways is considered little more than hypocrisy, not an exercise in artistry. The digital world churns; Twitter is not an arena known for reflection. Semicolons, then, are snottily elitist and shadily indirect.
</p>

<p>
	 
</p>

<p>
	Like many fading species, the semicolon has been usurped by a more violent, adaptable rival. “We live,” says Cecelia Watson author of Semicolon, “in the Era of the Dash.” It’s an accurate observation. The dash is brutal, unsympathetic, slashing, and impossible to be confused about — it takes you, frictionlessly, to the point. The dash invites no ambiguity and wastes no time. The punctuational equivalent of tearing a heart from a chest.
</p>

<p>
	 
</p>

<p>
	To read back those writers who put the semicolon to best use, like Jane Austen, or Virginia Woolf, is to enter a world where time is abundant. The OED describes the semicolon as “indicating a pause… more pronounced than that indicated by a comma.” The pronounced pause is where the real beauty of a semicolon lies. You can feel it in one of Woolf’s greatest sentences, as she describes Clarissa Dalloway hearing Big Ben: “First a warning, musical; then the hour, irrevocable.”
</p>

<p>
	 
</p>

<p>
	Put a dash where the semicolon is there and a whole moment in time and feeling would evaporate. The loss of such moments is what the end of the semicolon signals.
</p>

<p>
	 
</p>

<p>
	<strong><a href="https://unherd.com/thepost/the-melancholy-decline-of-the-semicolon/" rel="external nofollow">Source</a></strong>
</p>
]]></description><guid isPermaLink="false">3494</guid><pubDate>Sat, 27 Nov 2021 14:13:35 +0000</pubDate></item><item><title>Scientists use seismic noise to image first hundred meters of Mars</title><link>https://nsaneforums.com/news/general-news/scientists-use-seismic-noise-to-image-first-hundred-meters-of-mars-r3488/</link><description><![CDATA[<header>
	<h2 itemprop="description">
		Mars' winds create enough noise to see what's underneath the InSight lander.
	</h2>

	<p>
		<img alt="NASA_InSightArm_CROPPED-800x560.png" class="ipsImage" data-ratio="75.10" height="503" width="720" src="https://cdn.arstechnica.net/wp-content/uploads/2021/11/NASA_InSightArm_CROPPED-800x560.png">
	</p>
</header>

<section>
	<div itemprop="articleBody">
		<figure>
			<figcaption>
				<div>
					InSight places a wind shield over its seismometer.
				</div>

				<div>
					<a href="https://mars.nasa.gov/resources/22280/insight-deploys-its-wind-and-thermal-shield/?site=insight" rel="external nofollow">NASA/JPL-Caltech</a>
				</div>
			</figcaption>
		</figure>

		<p>
			NASA's InSight lander installed a seismograph on Mars, and the marsquakes it detected have helped us <a href="https://arstechnica.com/science/2021/07/marsquakes-illuminate-what-lies-beneath-the-sands-of-mars/" rel="external nofollow">map the planet's interior</a>. This data provides the big picture of Mars' internals—how big the core is, whether anything is molten, and so on. But it doesn't capture the small details, like what the ground immediately below InSight looks like.
		</p>

		<p>
			 
		</p>

		<p>
			This week, researchers described how they've managed to find quiet periods on Mars that lets them image closer to the surface. The results, combined with some nearby surface features, reveal that InSight is likely above two large lava flows, separated by layers of sediment.
		</p>

		<h2>
			Be very quiet
		</h2>

		<p>
			Marsquakes aren't useful for sorting out local features. If their seismic waves arrive from far enough away, then their behavior is mostly influenced by the materials they spent most of their time traveling through. If the marsquake happens nearby, then things are too energetic to make out the fine details caused by local features. So, in order to look at the local geology, you need to look at the background seismic noise that's constantly being picked up by InSight.
		</p>

		<p>
			 
		</p>

		<p>
			On Earth, most of the seismic noise is generated by either human activities or the oceans. But Mars lacks both of these noise sources, and its background is dominated by the wind interacting with features on Mars.
		</p>

		<p>
			 
		</p>

		<p>
			But when the data was examined at times of day when winds were generally high, the noise turned out to be dominated by frequencies that were produced by the wind interacting with the lander itself. So the researchers focused on what was early evening, Mars time, when the winds tended to die down. At that point, most of the seismic noise is generated by weak winds interacting with nearby geology rather than with the lander itself.
		</p>

		<p>
			 
		</p>

		<p>
			Geologists have used seismic noise to reconstruct features on Earth by comparing the horizontal and vertical components of the noise. This is a process that can be consistent with a large collection of potential structures near the surface of Mars. To constrain the list of possibilities, the researchers focused on features that showed up in the majority of potential solutions. They also looked at the rocks exposed in nearby craters to search for visible features that correlated to the things their models were suggesting might exist.
		</p>

		<h2>
			What’s underneath
		</h2>

		<p>
			Closest to the surface, the regolith of Mars is formed by dust and rock fragments produced by impacts. It appears to be only 1.5 meters thick, although the researchers caution that the data on the uppermost 20 meters of material is very uncertain. By three meters below the surface, there appears to be a layer of volcanic rock, formed by major eruptions in Mars' distant past.
		</p>

		<p>
			 
		</p>

		<p>
			Below that, from roughly 30 meters to 80 meters (these figures are pretty inexact), is another layer of material where seismic signals move slowly. The researchers conclude this is likely to be a layer of sedimentary rock. Below that are further volcanic deposits.
		</p>

		<p>
			 
		</p>

		<p>
			The researchers conclude that the deepest volcanic deposits date back to the Hesperian, a period of widespread volcanic activity that ended over 3 billion years ago. The overlying sediment deposit formed while Mars experienced cold, dry conditions similar to its present state. After it consolidated, and sometime during Mars' Amazonian period, additional eruptions covered the sediments. Since then, impacts and Mars' winds have deposited a layer of loose material on top of the volcanic layers.
		</p>

		<p>
			 
		</p>

		<p>
			Obviously, all of this is consistent with what can be observed in nearby craters. Still, it's impressive how much information the researchers were able to extract from just a bit of noise.
		</p>

		<p>
			 
		</p>

		<p>
			Nature Communications, 2021. DOI: <a href="http://dx.doi.org/10.1038/s41467-021-26957-7" rel="external nofollow">10.1038/s41467-021-26957-7</a>  (<a href="http://arstechnica.com/science/news/2010/03/dois-and-their-discontents-1.ars" rel="external nofollow">About DOIs</a>).
		</p>

		<p>
			 
		</p>

		<p>
			Listing image by <a href="https://mars.nasa.gov/resources/22280/insight-deploys-its-wind-and-thermal-shield/?site=insight" rel="external nofollow">NASA/JPL-Caltech</a>
		</p>
	</div>
</section>

<p>
	 
</p>

<p>
	 
</p>

<p>
	<a href="https://arstechnica.com/science/2021/11/scientists-use-seismic-noise-to-image-first-hundred-meters-of-mars/" rel="external nofollow">Scientists use seismic noise to image first hundred meters of Mars</a>
</p>
]]></description><guid isPermaLink="false">3488</guid><pubDate>Thu, 25 Nov 2021 23:23:59 +0000</pubDate></item><item><title>Will glow-in-the-dark materials someday light our cities?</title><link>https://nsaneforums.com/news/general-news/will-glow-in-the-dark-materials-someday-light-our-cities-r3487/</link><description><![CDATA[<header>
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		Photoluminescent substances could be applied to sidewalks, streets, and buildings.
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			Around the year 1603, Italian shoemaker and amateur alchemist Vincenzo Casciarolo tried smelting some especially dense stone he had found on the slopes of Mount Paderno, near Bologna. No gold, silver, or other precious metals resulted as he had hoped. But after the stone had cooled, Casciarolo discovered something interesting: if he exposed the material to sunlight and then took it into a dark room, the stone would glow.
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			That "Bologna Stone" was the <a href="https://www.schweizerbart.de/papers/ejm/detail/24/78460/The_Bologna_Stone_history_s_first_persistent_lumin?af=crossref" rel="external nofollow">first artificially prepared, persistently luminescent substance</a>. Many more were to follow—and today, persistent luminescent materials are used for decorations, emergency lighting, pavement markings, and medical imaging.
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			Someday they might give us glowing cities that stay cooler and use less electricity.
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			A <a href="https://www.annualreviews.org/doi/10.1146/annurev-matsci-091520-011838" rel="external nofollow">new generation of luminescent materials</a> has the potential to cool cities by re-emitting light that would otherwise be converted into heat. They might also cut down on energy use, since luminescent sidewalks, glowing road markers, or even glowing buildings could replace some street lighting. Already, some cities in Europe have installed glowing bicycle lanes, and some researchers have studied using <a href="https://www.jstage.jst.go.jp/article/easts/11/0/11_1726/_article" rel="external nofollow">glowing paint for road markings</a>.
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			<img alt="glow-in-dark-cities-1600x600-640x360.gif" class="ipsImage" data-ratio="56.25" height="360" width="640" src="https://cdn.arstechnica.net/wp-content/uploads/2021/11/glow-in-dark-cities-1600x600-640x360.gif">
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					The Van Gogh bike path in Eindhoven is inspired by the artist's painting The Starry Night. Similar glow-in-the-dark paths and roads could eventually save energy for lighting while cooling cities. (Enlarge to animate this GIF.)
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					<a href="https://studioroosegaarde.net/stories" rel="external nofollow">Daan Roosegaarde / studioroosegaarde.net</a>
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			"It's better for the environment," says Paul Berdahl, an environmental physicist now retired from Lawrence Berkeley National Laboratory in Berkeley, California. "If the technology can be improved, we can use less energy... It's a worthwhile thing to do."
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			The Bologna Stone, a form of the mineral baryte, fascinated natural philosophers at the time,] but was never especially useful. But in the 1990s, chemists developed new types of persistent photoluminescent materials, such as strontium aluminate, that maintained a strong glow for hours after exposure to light. Most of these new materials give off a blue or green glow, although a few glow yellow, red, or orange.
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			Such photoluminescent materials work by "trapping" the energy of a photon and then re-emitting that energy as lower-wavelength light. Sometimes the light is emitted immediately, such as in a fluorescent light bulb. Other materials, which are called persistently luminescent, store the energy longer and emit it more slowly.
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			<img alt="G-luminescent-materials-alt-640x418.png" class="ipsImage" data-ratio="65.31" height="418" width="640" src="https://cdn.arstechnica.net/wp-content/uploads/2021/11/G-luminescent-materials-alt-640x418.png">
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					More than 250 kinds of luminescent materials have been identified. Above they are grouped by a) the trace materials that act as the luminescent center; b) the host compound; and c) the color the material emits.
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			These materials that glow strongly for hours open possibilities, such as "glow-in-the-dark" cities lighted by luminescent pavements and buildings. Since <a href="https://www.sciencedirect.com/science/article/abs/pii/S0959652617329876" rel="external nofollow">19 percent of all global energy use is for lighting</a>, and in Europe <a href="https://publications.jrc.ec.europa.eu/repository/handle/JRC115406" rel="external nofollow">about 1.6 percent specifically for street lighting</a>, the potential energy savings are large, write building engineer Anna Laura Pisello and colleagues <a href="https://www.annualreviews.org/doi/10.1146/annurev-matsci-091520-011838" rel="external nofollow">in the 2021 Annual Review of Materials Research</a>.
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			One problem with the approach is that most luminescent material won't glow all the way through the night. Better materials could help solve that problem, says Pisello, of the University of Perugia, who studies energy-efficient building materials. In the meantime, existing materials could be combined with electric lighting that would come on long enough to recharge the road markings before switching off again.
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			Luminescent paint could also provide outdoor area lighting. Pisello's lab developed such a glow-in-the-dark paint and, <a href="https://knowablemagazine.org/do/10.1146/knowable-111121-2/full/%20https://iopscience.iop.org/article/10.1088/1742-6596/1343/1/012198" rel="external nofollow">in a 2019 report</a>, simulated what would happen if they painted a public path near a railway station with it. By glowing throughout the night, the paint would reduce energy needed for lighting by about 27 percent in the immediate area, the scientists found.
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			If this conjures worries of entire cities glaring throughout the night and adding to <a href="https://knowablemagazine.org/article/living-world/2018/there-goes-night" rel="external nofollow">harmful light pollution</a>, Pisello says that is unlikely. Luminescent materials would likely only replace existing lighting, not add to it. The color of the glowing materials could be chosen to avoid the blue frequencies that have been found especially harmful to wildlife.
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			Luminescent materials could also help fight what is known as the urban heat island effect. Rooftops and pavements absorb energy from the Sun and emit it as heat, driving city summer temperatures an average of 7.7 degrees Celsius higher than in the surrounding countryside. The high temperatures are a potential health hazard and also result in more energy being used to cool buildings.
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			One increasingly common solution is to use "cool" materials that reflect light, such as white paint and light-colored asphalt. It turns out that adding luminescent materials can help even more.
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			<img alt="P-smart-pavement-before-after.gif" class="ipsImage" data-ratio="120.27" height="540" width="364" src="https://cdn.arstechnica.net/wp-content/uploads/2021/11/P-smart-pavement-before-after.gif">
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					Anna Laura Pisello and colleagues at the University of Perugia are trying to create practical pavements that glow in the dark. They are experimenting with different luminescent substances and testing how to add them to pavement material to get the best performance and durability. Above are samples of luminescent materials and a paving stone in which they have been embedded.
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					Anna Laura Pisello
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			At the Lawrence Berkeley Lab, Berdahl and his <a href="https://www.sciencedirect.com/science/article/abs/pii/S0927024816301660" rel="external nofollow">team experimented with synthetic ruby</a>, a material that is luminescent while in sunlight, to make colored coatings that stayed cool. In an early experiment, they reported that a ruby-pigmented surface stayed cooler in the Sun than a similarly colored material without the special pigment.
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			Pisello's lab went one step further and <a href="https://www.sciencedirect.com/science/article/pii/S0038092X20303388" rel="external nofollow">added several persistently luminescent materials</a>—ones that stored light energy and gave it off slowly—<a href="https://www.sciencedirect.com/science/article/pii/S0038092X20303388" rel="external nofollow">to concrete</a>. Compared with non-luminescent surfaces of the same color, the best of them lowered the surrounding air temperature on sunny days by up to 3.3° C.
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			"You can make [a surface] as reflective as possible. But can you go beyond that? The idea is that maybe you can go a little bit beyond that using persistent luminescence as another way to transfer energy out... It is interesting," says Patrick E. Phelan, a mechanical engineer at Arizona State University who <a href="https://www.annualreviews.org/doi/10.1146/annurev-environ-102014-021155" rel="external nofollow">co-authored a paper on the urban heat island effect</a> in the Annual Review of Environment and Resources.
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			There are 250 known luminescent materials, many of them not yet studied for practical applications. Pisello says there is a potential for glowing paints and pavements that last longer and shine brighter in more colors.
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			"In the short term, the best and easiest solution is to improve what we already have," she says. That includes tweaking materials so that they give out light longer, more strongly, or in different colors, and making sure they continue to work in real-world environments.
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			In the longer term, she adds, new classes of engineered materials could work even better. For instance, one could turn to "quantum dots"—tiny semiconducting particles that can be made to glow and that are already <a href="https://pubs.rsc.org/en/content/articlelanding/2013/an/c3an36705c" rel="external nofollow">used in biological imaging</a>—or perovskites, materials used in solar cells that are also being studied for their luminescent properties.
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			<a href="https://knowablemagazine.org/action/doSearch?DOResourceTypeId=knowable&amp;sortBy=earliest&amp;startPage=&amp;text1=Kurt%20Kleiner%20" rel="external nofollow">Kurt Kleiner</a> is a freelance science journalist based in Toronto.
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			This story originally appeared on <a href="https://knowablemagazine.org/article/technology/2021/will-glow-in-the-dark-materials-someday-light-our-cities" rel="external nofollow">Knowable Magazine</a>.
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<p>
	<a href="https://arstechnica.com/science/2021/11/will-glow-in-the-dark-materials-someday-light-our-cities/" rel="external nofollow">Will glow-in-the-dark materials someday light our cities?</a>
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]]></description><guid isPermaLink="false">3487</guid><pubDate>Thu, 25 Nov 2021 23:21:26 +0000</pubDate></item></channel></rss>
